10 Best Vrbo Vacation Rentals In San Diego's Little Italy Neighborhood, California - Updated 2022

vrbo san diego little italy
Ruth Alexis
Ruth Alexis 

Little Italy is a chic neighborhood in San Diego, California, known for its indie music venues and great Italian food. While in San Diego, visiting Little Italy is a must for any foodie, as it is dotted with great pizza joints and farmer’s markets selling fresh seafood and produce. At the same time, those looking for up-market shopping opportunities should also head down to Little Italy, where a wide range of boutique stores and luxury shopping malls are available for visitors to shop till they drop. Looking for the best place to stay during your next trip to San Diego, California? Below are 10 of the best Vrbo accommodations in San Diego’s Little Italy, that you must check out.

1. Stylish loft with private patio (from USD 169)

This one-bedroom loft accommodates up to four people, making this accommodation option perfect for small families and groups of friends. This quaint loft comes with access to two private patios, where visitors can have a late night drink and chat with friends while enjoying the warm San Diego breeze. Nearby, there are wonderful restaurants and entertainment spots within a short walk from the apartment.

NEW!! Stylish Little Italy Loft with 2 Private Patios!
35 reviews  Wifi Available
condo 6 Guests 1 Bedroom 1 Bathroom

Accommodates: 6
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 30 days before check-in.

2. Luxury bungalow (from USD 338)

This three-bedroom bungalow is located in the heart of Little Italy, just a stone’s throw away from a wide range of shopping and dining options. Amenities in the bungalow include free Wifi, cable television, private parking space for up to three cars and a fully equipped kitchen. An extra perk of this bungalow is its large balcony on the second story, a perfect spot for a cup of coffee in the morning.

Spanish-Style Home in the Heart of Little Italy w/ 3 Patios & Garden
26 reviews  Wifi Available
House 6 Guests 3 Bedrooms 2 Bathrooms

Accommodates: 6
Minimum Nights: 2
Refund Policy :

Top guest reviews
Amenities & Room:
everything we needed to cook was in the kitchen
The beds were very comfortable
There was also mold in the blender
The bedrooms were inviting and comfortable Great kitchen
Kitchen and living room area was nice and spacious
The property was very clean
Very clean and well stocked and very comfortable
The house was very clean fresh towels for everyone and
The house had lovely decor and was very homey and inviting
The vacation rental was very clean
The information about the construction noise on the property next door is correct
They had a very pleasant outside sitting area
I was very happy with the location
I was very happy with the location
I was very happy with the location
Specially if you are from outside America that roku is not available
We walked to Little Italy several times lots of great restaurants
We walked to Little Italy several times to eat and walked to the Midway Museum Balboa Park
everything is within minutes (walking)
We also had a nice walk to the Midway Museum Balboa Park was a nine minute drive
Read more reviews

3. Brand new modern loft (from USD 269)

This brand-new space includes many great amenities and appliances, including two flat-screen televisions, a grill on the patio and a six-foot champagne glass for a relaxing drink at the end of a long day of sightseeing. The kitchen is fully stocked with all the essential equipment, making it suitable for guests wanting to have a quiet night in with some home-cooked food. Just a short 15 to 20-minute walk away are many key places of attraction, including the San Diego Convention Center, Petco Park and the San Diego Zoo.

Hidden gem in the heart of Little Italy in downtown San Diego!
29 reviews  Wifi Available
condo 12 Guests 2 Bedrooms 1 Bathroom

Accommodates: 12
Minimum Nights: 3
Refund Policy : 100% refund if you cancel at least 30 days before check-in.

4. Cozy one-bedroom loft (from USD 175)

This modern one-bedroom loft is decorated in a minimalist style and was designed by Jonathan Segal, one of downtown San Diego’s most prominent and innovative architects. A key feature of this loft is its private patio with seating and a grill, where guests can enjoy a barbecue after a long day of sightseeing. Found in Little Italy, the apartment is close to various restaurants and entertainment venues which you can explore.

Welcome to the heart of Little Italy in downtown San Diego!
38 reviews  Wifi Available
condo 6 Guests 1 Bedroom 1 Bathroom

Accommodates: 6
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 30 days before check-in.

5. Cozy apartment in the city center (from USD 168)

This four-bedroom apartment is located on the first level of a detached home in the middle of Little Italy. Included in the price is a secure, assigned parking space located in a parking garage right next door. One queen bed and two twin beds are available for the guests’ use, making this apartment perfect for small families with children. A wide range of entertainment options is available within this apartment, from a pool table to a library of videos and CDs for use with the two televisions provided.

Historic Gem in the Heart of Little Italy!
191 reviews  Wifi Available
Apartment 4 Guests 2 Bedrooms 1 Bathroom

Accommodates: 4
Minimum Nights: 3
Refund Policy : 100% refund if you cancel at least 30 days before check-in.

Top guest reviews
the accommodations and hosts were great
anthony is a perfect host
anthony was so attentive to us; he checked in and made sure we had everything we needed
anthony was a very gracious and responsive host
anthony was a great host and recommended several restaurants and sights to visit
close to all the great features of downtown gaslamp district and petco park
the location itself is amazing right in little italy and walking distance to downtown
recommend staying on a saturday so you can partake in the farmers' market taking place that morning
the location was wonderful and is as described
anthony has a great place in a great location
Read more reviews

6. Spacious studio apartment

This spacious studio apartment was built with open-concept living in mind. The kitchen, bedroom and living area are all found within the same open area, with a blue and white decor giving this studio apartment a classy and serene feel. Some of San Diego’s best dining options are found within walking distance of this apartment, like the Ironside Fish & Oyster and Juniper & Ivy restaurants. The Mercato, a weekly farmers’ market, also opens steps away from this apartment complex. The friendly host is open to being contacted 24/7.

Sonder | State Suites | Quaint Studio + Patio
San Diego, CA, US
5 reviews
Apartment 0 Bedrooms 1 Bathroom
Top guest reviews
Pleasant Easy Would book again a
Enjoyed almost everything about the stay
Only downfall was parking Expensive and exhausting to search for daily
Clean within walking distance to great restaurants and very modern
well if u want to cook Walked to the zoo
quick uber to oldtownWe enjoyed our stay
Sonder rentals are the best and this place was everything we expected
We liked this place its modest and very clean
Read more reviews

7. Spacious apartment

This spacious apartment is located a stone’s throw away from many exciting places of interest scattered around Little Italy, including the San Diego Zoo and San Diego shopping district. The two-bedroom apartment can accommodate up to six people, making this a spacious and modern option for larger families and groups of friends.

No need for car, walking anywhere and close to airport, trolley, train
14 reviews
townhome 2 Bedrooms 3 Bathrooms
Top guest reviews
Amenities & Room:
the condo spacious with two large bedrooms
You go up one flight to the two bedrooms
You go down one flight to the laundry
the view of the bay from the fifth floor rooftop Lounge chairs and tables and a BBQ were available to enjoy All amenities provided made our stay very pleasant
The condo was spacious and close to everything including the trolley the train station the airport and Gaslamp
No need for car as the public transportation was readily available
A great clean and well setup condo with wonderful parking
But all in all
condo worked great for us especially with the 2 parking spaces included with the rental kitchen was updated and stocked well Slight noise with a work out studio located below the unit but didn'...
It was a pleasure for us to have the city right at hand along with that fantastic deck to enjoy the sunsets
We parked the car in the secure underground garage the first day and didn't use it again until we reluctantly left the condo and San Diego
What a treat to walk 3 minutes to so many great eateries
It is in a great location steps away from the main drag of Little Italy
so easy to get everywhere in San Diego
It is a great location in Little Italy within an easy walk to all the area restaurants and to the trolley
We could walk to everything within 10 minutes Coronado and Balboa park
Read more reviews

8. Modern condominium in the heart of Little Italy

This spacious one-bedroom loft in the heart of Little Italy is equipped with a host of hi-tech amenities for your enjoyment. These include a flat-screen television, Blue Ray DVD and high-speed wireless internet. A key feature of this loft’s interior design is its floor-to-ceiling windows in the living room, allowing warm natural light to filter through the entire living space. Other amenities in the condominium complex include an outdoor patio, a fitness room and a heated spa.

Hi Tech Urban Escape~Steps To Bay, Trolley in Heart of Little Italy!
1780 Kettner Blvd
12 reviews
condo 1 Bedroom 2 Bathrooms

9. Waterfront condominium

This spacious condominium is located on the eighth floor of a highrise condominium, with spectacular views of Waterfront Park and the ocean beyond. It is also within walking distance of the San Diego Convention Centre, making this accommodation option perfect for businessmen or other attendees of one of the many conventions that are held at the convention center throughout the year. For travelers keen on enjoying a shopping or dining spree, Horton Plaza and Street Faire are just a stone’s throw away.

180 Degree Views! Heart of Little Italy! Walk or ride Trolley to All!
300 W. Beech Street
4 reviews
condo 2 Bedrooms 2 Bathrooms

10. Luxury modern house

luxury modern house
Source: Vrbo

This five-story home includes four bedrooms and a rooftop garden on the fifth floor, where guests will be treated to amazing views of a river, ancient church across the street and more. On the second floor is a patio, where guests can relax and soak in some sun in the afternoons. A wide range of bedding options is available in this house, allowing it to accommodate as many as 10 people. From bunk beds, blow up mattresses to king-sized beds, your family and friends will be assured a comfortable stay in this modern home.

A Modern 4-story Work Of Art Located In The Heart Of Little Italy
San Diego, CA, US
4 Bedrooms 3 Bathrooms

Delightful accommodation options

With so many amazing accommodation options to choose from in Little Italy, San Diego, it is a wonder how you will be able to pick just one option for your next trip. From luxury mansions to cozy apartments, almost all of these living options are located conveniently in the heart of Little Italy and within close distance to many key places of attraction. Be sure to check out the above 10 best Vrbo accommodation options before your next trip to Little Italy.

Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.

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Ruth is a freelance writer and novelist who loves snuggling, skating, and all things matcha.

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