6 Best Vrbo Vacation Rentals In San Francisco's Mission District - Updated 2024

vrbo san francisco mission district
Samantha
Samantha 
Updated
| 4 min read

San Francisco is a uniquely American city with several romantic places that hold stunning Pacific-facing views and a Mediterranean-like climate with many exciting things to do for free. San Francisco’s Mission District is a historically Latino community that recently has undergone major gentrification due to the dot-com bubble. Whether viewed as good or bad, these changes have brought new energy and businesses to the Mission District. From hipster-vibe dive bars to boutique fashion stores, the Mission District is a fun and trendy place to stay when visiting San Francisco. From highlights such as Dolores Park to endless eateries to historical sights such as Mission Dolores, there is something for everyone in the Mission District. Read below to see the top Vrbo vacation rental in San Francisco’s Mission District, and get California dreaming.

We handpicked these listings carefully, considering (wherever possible) Superhost status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on April 07, 2024.

1. Intimate garden retreat in the heart of the city (from USD 85)

Discover a beautifully transformed one-bedroom long-term rental in the lively Mission District of San Francisco, accommodating up to four guests. This intimate garden retreat is available for stays of 30 nights or more, featuring a queen bed, double futon, and a tranquil private garden. The full kitchen and comfortable bathroom with a rain shower ensure a welcoming experience.

Nearby, explore eclectic cafes, shops, and renowned landmarks. Public transit is readily accessible, though parking is limited. This non-smoking, child-friendly space does not allow pets or provide parking, ensuring a serene stay in the heart of the city.

Stayed at this property?
San Francisco, California, United States
1.56 km (1.0 mi) from Dolores Park
Apartment 4 Guests 1 Bedroom 1 Bathroom

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2. Stylish two-bedroom apartment (from USD 142)

Experience the charm of San Francisco’s Mission District in this stylish two-bedroom apartment, perfect for accommodating up to six guests. This vacation home for rent in San Francisco’s Mission District boasts queen-sized beds, a fully equipped kitchen with modern amenities, and a cozy living area with a flat-screen TV and WiFi. Enjoy the shared backyard for social gatherings, complete with a barbecue grill. Although pet-friendly, guests are advised to consider the tight fit of the private garage suitable for small to mid-sized vehicles.

Stayed at this property?
San Francisco, California, United States
635 meters (0.4 ft) from Dolores Park
Apartment 6 Guests 2 Bedrooms 1 Bathroom

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3. One-bedroom oasis in Mission District (from USD 326)

If you’re traveling solo and seeking calm within San Francisco, or if you are a couple looking for a romantic getaway, this accommodation in the Mission District of San Francisco awaits your arrival. The kitchen can accommodate light cooking, but with cute cafes and restaurants within walking distance, you may want to eat out. A zen-like aesthetic helps keep the energy calm, as well as a lovely backyard. With the Mission District reputedly having the best weather in all of San Francisco, take advantage of the outdoor space. You will love this tranquil home for two.

Stayed at this property?

1.65 km (1.1 mi) from Dolores Park
64 reviews   Wifi Available
Apartment 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2
Minimum Nights: 1
Refund Policy : 100% refund if you cancel at least 60 days before check-in.

Top guest reviews
Amenities & Room:
The living room is cozy and has internet TV so Netflix and other channels
The kitchen does not have cooking facilities
Both the living room and the bedroom (downstairs) have large windows overlooking the lovely private backyard garden accessible from both levels
The apartment was cheerful quiet and spotless; the bed was really comfortable
The 2 story is apartment is spacious and comfortable
Cleanliness:
The property was extremely clean spacious and very private
Her property is immaculately clean
very well decorated & very spacious for 2
the bathroom immaculate and the towels very ample and soft
and we hope to stay in her apartment again
Host:
Elizabeth was a wonderful host Very responsive and provided a beautiful home for our long weekend getaway
She also had awesome home made cookies and granola
She also was very accessible and responsive to any questions we had
She was also available for any questions we had about the city even before we got there
and she had ice for me waiting
Location:
The location is great too
This property is located close to many wonderful restaurants and bakeries many of them located up and down
There are also good places to grab food only a few blocks from the property
and we used Lyft to get around the city
The area has improved over the years and has some amazing places to walk to eat drink and shop
Read more reviews
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4. Immaculately remodeled four-bedroom apartment (from USD 200)

This gorgeous rental apartment in the Mission District of San Francisco has recently been remodeled with a fully equipped kitchen, sleek bathrooms, and spacious bedrooms. A long-term rental, visitors must stay at least 30 nights. Quiet, yet close to public transportation, shops, coffee shops, and restaurants, this apartment has it all. Check out views of downtown San Francisco and feel like you’ve really arrived.

Stayed at this property?
San Francisco, California, United States
1.34 km (0.9 mi) from Dolores Park
Wheelchair accessible Visual Aid: Braille
Apartment 4 Guests 1 Bedroom 1 Bathroom

Top guest reviews
Amenities & Room:
In the bedrooms towards the street sensitive people need earplugs
great roof top views and big enough to sleep all the guests and small enough to enjoy each other's company
The king size beds were really comfy though with nice thick duvets
just bar stools at the kitchen bar so while the kitchen is large and the apartment can hold a large family
You will do real good right here
Cleanliness:
The apartment was nice and clean and there were towels and bathroom amenities in abundance Since we didn't want to share beds
even though the apartment was just cleaned (it was very clean in teh afternoon )
but I wouldn't bother to look
Host:
Our hosts were very communicative and answered all of our questions
so hopefully other groups can utilize in the future
so we bought Solo cups at the store
Spotlessly clean well furnished and great location
The communication with the property manager was always prompt and super helpful
Location:
(not a big deal)
There was not enough glasses to drink from (only wine glasses)
It was quiet easy on for freeway and Market Street access and close to grocery stores and many other places to eat etc
The apartment is a very short walk away from the Market Street streetcar which goes directly to the Ferry Terminal Building and the Wharf
There is also a Whole Foods and Safeway within 5 minutes walk
Read more reviews
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5. Sleek executive home in Mission Area (from USD 633)

If you seek an aesthetic that is clean, modern, yet natural, this large home is perfect for you. It sleeps up to six guests in the three bedrooms. Meant for long-term rentals only, this home is perfect for someone commuting downtown for work, and to return home to the peace of their own space. Set within the artistic community of the Mission District, explore the murals that enliven the neighborhood.

Stayed at this property?

397 meters (0.3 ft) from Dolores Park
1 review  
House 6 Guests 3 Bedrooms 5 Bathrooms

Accommodates: 6
Minimum Nights: 30
Refund Policy : 100% refund if you cancel at least 60 days before check-in.

Top guest reviews
Host:
It is a beautifully designed home with nice finishes
Location:
The neighborhood was a little gritty
Read more reviews
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6. Elegant two-bedroom for long-term stay

This classy and affordable two-bedroom apartment sleeps four in a remodeled Victorian unit. Found in a central location in the Mission District, it is easy to walk to entertainment, food, and shopping. A lovely backyard patio makes breakfast in the open air, or cocktails at sunset, an option. Two BART stations are nearby, making travel and commuting easy. This apartment is advertised for long-term rentals only (30-day minimum), although if contacted, the owner is willing to consider shorter stays.

Stayed at this property?

907 meters (0.6 ft) from Dolores Park
4 reviews   Wifi Available
Apartment 4 Guests 2 Bedrooms 1 Bathroom

Accommodates: 4
Minimum Nights: 30
Refund Policy : 100% refund if you cancel at least 14 days before check-in.

Top guest reviews
Amenities & Room:
The kitchen and bathroom are very modern and the appliances worked perfectly
We comfortably fit the four beds in the two bedrooms and
It was a delight to meet them
so we could feel at home in the area
Host:
But most wonderful of all was Monica and her husband who are such welcoming hosts
Our family was traveling through SanFransisco and had a terrific couple of days exploring the city
Monica was so accommodating in helping us find a comfortable sleeping arrangement
The yard in the back is teaming with plants and the entrance is also charmingly decorated with succulents and all kinds of beautiful plants
They went out of their way to make us feel comfortable and safe in the area
Location:
The apartment is located on a clean quieter street a very short walk away from excitement of the more major streets in the Mission
The Mission District is a very fun neighborhood to stay in and Monica gave us so many suggestions and advice
Read more reviews
Oops, this listing is currently inactive. Check out these alternative properties in the same location.
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Beautiful accommodations in the Mission District

These beautiful Mission District accommodations will have you plotting your adventures to San Francisco. Whether you seek a short-term rental or a long-term stay, there are options for every need, on this list. Enjoy all that the Mission District offers with these accommodations, which are an easy walking distance to the action, or jump on a bus to get to other parts of sunny San Fran. With so many wonderful places to choose from, you’re ready to book today!

Frequently asked questions about Vrbo vacation rental in San Francisco's Mission District


Any must-sees we missed? Tell us about them in the comments section or write a post here to help out fellow travelers!
Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.

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Raised in the woods of Northern Wisconsin, adventure pulses through Samantha's veins. Among the most notable adventures have been teaching agriculture in Kenya, WOOFing in Turkey, and learning...Read more

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