The bustling metropolis of Greenville, a renowned world famous destination for cyclists, beckons visitors with its beautiful tree-lined Main Street, nice hotels, boutiques, exciting restaurants and bars, performance venues, great shopping, a river with waterfalls right in the heart of downtown, and more. Situated in the foothills of the Blue Ridge Mountains, Greenville offers all the big city amenities and small town pleasantries. The Falls Park, Swamp Rabbit Trail, Caesar’s Head and Jones Gap for hikes, photos and picnics, great museums, carriage and trolley rides, and mountain park right in town are some of the major attractions.
The special scavenger hunt on Main Street enthralls kids. The low cost of living and pleasant temperatures year-round make Greenville a hot destination for travelers. In order to feel comfortable, we recommend you stay at one of these following Vrbo accommodations:
We handpicked these listings carefully, considering (wherever possible) Superhost status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on October 11, 2025.
1. Downtown Greenville historic district vacation/corporate condo (from USD 79)
The condo is on a nice quiet street within walking distance of downtown. You can walk to the city center or catch the trolley. The condo offers lots of room in the master bedroom. The kitchen has everything you need to cook without having to go out.
The refrigerator is stocked with basic condiments, snacks, and breakfast food. The TV and the internet are great and the furnishings are fine. It’s adorable and very comfortable.
Greenville, South Carolina, United States
2.02 km (1.3 mi) from Falls Park on the Reedy
Top guest reviews
Host:
easy process and communicative owner is alway niceLocation:
this condo is in a great locationann's condo is on a nice quiet street within walking distance of downtownnice place great location and perfect ownerit’s a nice neighborhood for evening walks where everyone says hiin fact it was probably the best stocked place i've ever stayed inCleanliness:
condo was very clean& safeyour condo was clean and comfortable for a short or long term staya very clean and comfortable condo my husband and i enjoyed staying thereit was well stocked and cleanit was well stocked and super cleanRead more reviewsAmenities & Room:
the tv and internet were great and the furnishings finenice little apartment- perfect for a visit to greenvillethere were definitely moments we wanted an extra bathroomgreat space with lots of room in the master bedroomloved the historical neighborhood the apartment was in
2. Large one-bedroom place that is steps from Main Street (from USD 212)
This is a well maintained, beautiful, and spacious penthouse unit with a private terrace. The penthouse accommodates four people and has all the conveniences of home with a full kitchen and lots of open space to spread out for a few days or an extended stay. The bedroom has a king bed and the sofa pulls out to a queen size sleeper. While it is right in the center of town, it remains peaceful. The location is great with private parking and an easy walk to shops, restaurants, and trails.
Greenville, South Carolina, United States
335 meters (0.3 ft) from Falls Park on the Reedy
Top guest reviews
Host:
property owner very responsivethe owner was very easy to communicate with and the home was exactly as it was postedLocation:
great location to enjoy the towneasy walk to all the hot spotswe loved the location and walking to restaurants and shops of greenvillecan’t beat the location and the place is so nice and well appointedwould definitely rent again great location clean & comfortableCleanliness:
very clean and well stockedexceptionally clean updated and beautifulthe unit was very nicely appointed and cleanRead more reviewsAmenities & Room:
a beautiful apartment with a great outdoor terrace and terrific furnishings and accomodationsdecorated with style yet super comfortable
3. Fully furnished three-bedroom condo, 7 minutes from downtown Greenville
Conveniently located near several restaurants, parks and down town Greenville, the clean and comfortable condo is located on the third floor (no elevator) with a vaulted ceiling. The condo has a kitchen, dining room, living room, and hall. The master bed room has laminated flooring and the two-bed rooms have carpets. It has one designated parking space and ample space for visitor parking. The community pool is open from May to September.
Fully furnished three-bedroom condo, 7 minutes from downtown Greenville
Number of Guests: 6
4. One mile to downtown and Greenville Hospital System (from 117 avg/nightUSD)
Jennifer’s duplex is comfortable and beautifully decorated. The unit is clean and has everything you need for a home away from home. The set-up of this place is great with a fenced yard, conveniently located off of the back of the home, great for the dogs. There are wonderful streets nearby to walk with friendly neighbors.
One mile to downtown and Greenville Hospital System
Price: from 117 avg/nightUSD
Number of Guests: 2
5. Downtown guest cottage with free WiFi (from 129 USD average per night)
The guest cottage is very clean, well equipped, and well laid out. The pet-friendly fully furnished cottage features one bedroom with a queen bed and a walk-in closet. Amenities include cable TV, free WiFi, central air conditioning, a ceiling fan, extra blankets and pillows, fresh linens and towels, a fully equipped kitchen and free parking. It can accommodate a third person.
Downtown guest cottage with free WiFi
Price: from 129 USD average per night
Number of Guests: 3
6. Cozy and quaint, beautifully renovated, historic bungalow (from USD 121)
This bungalow has a charming front porch and spacious back deck with a picnic table and gas grill and two wonderful outdoor spaces. The kitchen has granite countertops and updated appliances. The master bed is very comfortable and the added closet system in the second bedroom provides enough space for the storage of clothes. Sabrina Simon the property manager is easily accessible and promptly takes care of any problems that arise during the stay.
Greenville, South Carolina, United States
1.67 km (1.1 mi) from Falls Park on the Reedy
7. Stylish one-bed, one-bath condo in historic brick building (from USD 214)
This peaceful and secure condo in the historic brick building at 100 West Court Street has exposed brick walls, granite counters, hardwood floors, and stainless steel appliances with a well-stocked kitchen. You can walk to all the Main Street shops and restaurants from this location. The modern, convenient, and clean condo is equipped with all the amenities you will need. Guests have access to parking in the parkade just steps away; the owner is quite cooperative and promptly addresses the concerns of the tenants.
Greenville, South Carolina, United States
439 meters (0.3 ft) from Falls Park on the Reedy
Top guest reviews
Host:
host was exceptionally responsiveowner was extremely helpful with every detailthe hosts really care about their guests and it showstricia was a great host and we had an awesome timewe had a fantastic experience with the host and the condoLocation:
wonderful condo in an excellent location in downtown greenvillethe location is in a perfect place to explore downtown greenvillethe location is close to the peace center and main streeteasy walk to all of downtownspectacular property and location that was perfect for our long weekend in greenville and clemsonCleanliness:
very clean and well equippedwonderful property - great location very clean and well maintainedRead more reviewsAmenities & Room:
the space is warm comfortable and convenient easy access through an adjoining garage
8. Two-bedroom, one-bathroom cottage near downtown Greenville (from 107 avg/night USD)
Within a short drive to the beautiful downtown Greenville, this beautifully decorated home is clean and well-maintained and has everything you could need. The quiet, safe, and convenient home have cozy and comfortable bedrooms and living spaces, as well as a dining room and a well-equipped kitchen. Lidia the property manager is quite prompt in responding to tenants’ requests.
Two-bedroom, one-bathroom cottage near downtown Greenville
Price: from 107 avg/night USD
Number of Guests: 6
9. Quiet neighborhood near downtown and airport
This is a charming, clean, well-located home in a nice neighborhood with all the things that you would need for a home away from home. The master bathroom has a walk in shower with three shower heads. The master bedroom is away from the other bedroom in a peaceful place and the living room TV is enormous. The kitchen is large and well-equipped; the dining room can accommodate more people if needed. Located near the city and restaurants, you have an entire house for less than the daily price of a hotel room.
4.85 km (3.1 mi) from Falls Park on the ReedyAccommodates: 8
Minimum Nights: 2
Refund Policy : 100% refund if you cancel at least 14 days before check-in.
Top guest reviews
Host:
shaw was very accommodating and a pleasure to communicate withalan was very responsive to all communicationLocation:
the location was greatthe location is great very close to local shopping and a short drive to greenville’s wonderful downtown areaideal location for our weekend furman singers reunionthe house is beautiful and very close to downtown greenvilleperfect for business or fun trip with it's quietCleanliness:
very clean and great communication from the ownerit was clean and all we hoped forthe house was spacious clean and well equippedthe house was very clean and has a fabulous master bathRead more reviewsAmenities & Room:
having the space made thing very comfortable and relaxing for everyone
10. Basement apartment with private entrance (from 88 avg/nightUSD)
Located just a couple of minutes from bustling downtown Greenville in a friendly neighborhood, the apartment is cozy, clean, quiet and very comfortable. The patio is relatively private in this basement apartment. It offers an opportunity to sit, relax, and watch the birds and squirrels scampering around while listening to the birds singing over a cup of tea. Being a basement apartment, it stays pretty cool and is pretty comfortable.
Basement apartment with private entrance
Price: from 88 avg/nightUSD
Number of Guests: 3
World famous destination for cyclists
The world famous destination for cyclists, Greenville beckons visitors with its beautiful street, nice hotels, boutiques, exciting restaurants and bars, performance venues, Falls Park, Swamp Rabbit Trail, and more.
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