Panama City is the cocktail of Central America with a mixture of cultures, races, and cuisines. You can find many exemplary seafood restaurants in Panama City where you can enjoy delicious prawns, scallops, lobsters, giant crabs, clams, and more. If you are a vegetarian, you can visit the vegetarian-friendly places to eat in Panama City. To ensure you have a memorable stay, we’ve sourced some of the finest vacation rentals in Panama City. No matter what type of property you’re looking for, we’ve got it covered, from luxury high-rise apartments to tropical cottages. Read on to learn about the top Airbnb vacation rentals in Panama City, Panama.
We handpicked these listings carefully, considering (wherever possible) Superhost status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on April 04, 2024.
1. Casa Santorini (from USD 274)
This stunning three-bedroom beachfront home enjoys a first-class view of the Caribbean, so you can sit back and enjoy the beauty of the Caribbean as you lounge in your hammock and watch the sunset. While guests at Casa Santorini can enjoy privacy, the property also boasts an excellent location, just 2-hours drive from the city.
The property has modern conveniences such as fast WiFi, laundry essentials, air-conditioning, and a fully equipped kitchen. The spacious back garden houses a grill, perfect for bbq nights with your loved ones. Guests who drive will be happy to know that free parking is available.
Snorkeling enthusiasts will be in for a treat, as Casa Santorini boasts a little reef within 100 meters (328.08 feet) of the house, so be sure to ready your swimming attire! Moreover, pets are allowed here, so don’t leave your furry friends behind!
Mention "Trip101" during your booking and enjoy a 10% discount! Click the link below to book now. Terms and conditions apply.
Top guest reviews
Amenities & Room:
wifi connection was very goodCleanliness:
it has everything you need and it was cleanHost:
also fransisco was very helpful so this week end was just perfectRead more reviewsLocation:
the place is beautiful right in front of the sea
Superhost
2. Casa Saema (from USD 140)
Have a pleasant stay in this gorgeous holiday apartment rental in the city’s historic district. You can beat the heat and enjoy a refreshing dip in the outdoor swimming pool set in a lush tropical courtyard. Relax on one of the poolside lounge chairs and enjoy the fresh air.
When not in the mood to dine out, you can use the fully equipped kitchen to prepare gastronomic delights. You can entertain yourself by watching TV or streaming movies and shows via free WiFi.
Top guest reviews
Amenities & Room:
we rented 2 units both were perfect plenty of room to eat sleep relaxapartment is well equipped very useful to have a machine machinealthough room d was slightly larger we loved room b directly in front of the poolbeautiful place with a beautiful poolCleanliness:
clean modern safe beautifulit’s a clean fresh and inviting oasis) it is clean spacious modern and was very easy to check intoHost:
he was so welcoming and kindhost was very communicative and jose on site was super helpful and kindowner and property manager was very helpful in making sure we had a great stayall with friendly staff and easy going vibebeautiful owners and jose is fabulousRead more reviewsLocation:
great location in casco viejothis place is perfectly locatednice location and safe and quietthe location was very central and jose was extremely helpfulit is located close to very good restaurants
3. Well-appointed studio apartment (from USD 46)
A delightful stay awaits you at this comfortable apartment within walking distance of the Pacific Ocean coast. It provides free on-street parking for your convenience.
The accommodation offers homelike amenities such as a fully stocked kitchen where you can whip up delicious recipes. You can stay connected to the world with complimentary high-speed WiFi. You’ll also find a dedicated workspace ideal for digital nomads. Watch your favourite Netflix shows on the HDTV or play board games to entertain yourself indoors.
Top guest reviews
Amenities & Room:
the apartment was better than the photos and the location was greatCleanliness:
the place was spotless and clean and jose was super responsive if i had any questionsthe place was clean with great technology and very good value for moneyHost:
great host that was super flexiblejose is attentive and caring hostthe host is a great person and is attentive to your needs 100% recommendedRead more reviewsLocation:
there are also mini shops/markets closer to the apartment that were good for grabbing quick things
4. 'Bocas' style city apartment (from USD 91)
What’s near: Natural Science Museum
This colourful ‘Bocas’ style apartment brings the tropical island to the heart of Casa Viejo. It comes complete with high ceilings and two bedrooms; one a double and the other one containing bunk beds for the little ones. It seems that this tropical blue, airy apartment has it all - from WIFI to air conditioning, and even enough room to bring your pets. All you have to do is get here and kick back in the hammock of this vibrant apartment and think about where your next adventure will take you.
Top guest reviews
Amenities & Room:
the balcony is better then any tvair conditioning worked great which is very necessarythe kitchen is sufficient and the balcony was enjoyableshower was great and ac works very well toocomfy beds great air conditioningCleanliness:
clean and great communication with ursulathe house was very clean and comfortablethe apartment itself is clean and adorablethe apartment was clean and had everything we neededthe apartment was clean and looked like the picturesHost:
ursula was a very informative host who was always ready to answer questionsshe was very helpful helping me plan and gave great tipsshe was really responsive too and helpful with questionsursula is a great host will stay again if given the chanceursula is a great hostRead more reviewsLocation:
location is great it is very close to restaurants bars and storesgreat location on the edge of cascogreat location for people watching and close to lots of fantastic bars and restaurantsthis place is in a great location in casco viejowithin walking distance of many cosco attractions and restaurants
5. Bay-side apartment (from USD 100)
What’s near: Panama City Bay
This modern, spacious loft is set in the most central of Panama City; only a few minutes from Panama City Bay - where you’ll find bars and restaurants; that is if you choose to leave this apartment. It comes equipped with a spacious bedroom with city views, a fully functional kitchen, WIFI and a comfortable living space. You will also have full use of the apartment complex’s communal areas: swimming pool, squash court, gym and steam room - ensuring that you can work off all of the indulgences that Panama City has to offer you.
Top guest reviews
Amenities & Room:
the wifi and cable tv worked perfectlyvery nice apartment with great amenitiesgreat loft location host amenities super fast wifiCleanliness:
super clean and comfortablethe apartment is very clean and feels well cared forgreat apartment that was very clean and centrally locatedit was nicely furnished clean and has secure accessHost:
carlos was a very good hostcarlos is an excellent hostcarlos is very nice and informativecarlos was extremely helpful with our check in processthe building is clean and the staff is efficient friendly and helpfulRead more reviewsLocation:
everything is within a 6-10 minute walking distance including the metro great restaurants casinos shopping etcthe location was great for us in a mixed use neighborhoodvery close to city sights and easy access to the freeways for road tripsvia espana has all manner of stores and shops including a super marketthe perfect place to stay while in panama city
6. Apartment in the sky (from USD 402)
What’s near: Habana Panama dance club
Have you ever dreamt of living the high-life with luxury living? Well now you can, quite literally, with this stunning, vibrant penthouse with 360° views of downtown Panama and the bustling Casa Viejo. This has got to be one of the most unique Airbnbs within the Panama City region - with exposed brick walls, a private pool, colourful living areas and large bedrooms that have each been individually designed.
I’d book this stunning Airbnb as soon as possible before the entire team at Trip101 beats you to it.
Top guest reviews
Amenities & Room:
beds were super comfy and air con worked greatfantastic building easy access ac cool dipping pool on deck and so much morethe rooftop deck and rooftop pool were a great place to relaxbeautiful and amazing apartment with stylish interiors & furniturestunning views from all 3 levels of the house extremely comfortable beds and a wonderful kitchenCleanliness:
aylin was an extremely helpful host check-in was seamless and the place was very clean when we arrivedHost:
alana & aylin were amazing hostsalana is a great responsive hostvery helpful hostalana and aylin are the most accommodating and helpful hostsaylin was the perfect hostRead more reviewsLocation:
the location is fantasticlocation is absolutely amazinggreat location and unique stylewalking distance to several great restaurantsgood place and great location too
7. Pacific Ocean apartment (from USD 60)
What’s near: Multicentro mall
If you’re looking for a beachfront Airbnb in Panama City, this is the place to be. Would you like to sleep in the sky in downtown Panama City? You can do that, thanks to this comfortable luxury apartment. There is nothing quite like gazing out over the surrounding skyscrapers and the Pacific Ocean from this apartment. This is the ideal place to stop if you’re in the city on a business trip or for a few days. It has style and unforgettable views - especially from the rooftop hot tub.
Top guest reviews
Amenities & Room:
the apartment was nice and the view is spectaculari still think apartment was nice i enjoyed my stayCleanliness:
great views centre of the city clean certainly s place to comeback tooHost:
its expensive but was worth the money reception guys are very friendly tooadriano and the staff at the complex were very helpfulRead more reviewsLocation:
love this location and the apartmentenjoyed the convenience of the locationfantastic place with a incinerable host
8. Tropical cottage in the city (from USD 85)
What’s near: Recreational Park Omar Torrijos
If city apartments aren’t your cup of tea and you prefer something a little more topical and cottage-like, then this Airbnb rental is just up your street. Sleep in tropical surroundings hearing nothing but the chirping of birds and the rustling of wildlife outside your window, knowing full well that you’re still in one of the most exciting cities in Central America. This one Queen bed / one sofa bed two-story ‘cottage’ has everything you need to make your stay in Panama City one to remember. With WiFi, a functional kitchen and a comfortable living space to enjoy the green, lush views around you, this is the ideal place to base yourself in a city such as Panama where you can enjoy tropical Central American vibes.
Top guest reviews
Amenities & Room:
perfect a/c system all the kitchen utensils one needs to cook and very good internet connectionthe a/c was beautiful as the temperature outside was 90+ degrees and very humidthe only issue was that the wifi wasnt working =( besides that i will definitely stay againthey did both agreed that the couch bed was plenty comfortable for them during our stay herethe sleeping area was great too and the bathroom was decent with hot waterCleanliness:
the space was clean and as advertised in the pictureseverything was clean and comfortable with enough room for four peoplepablo's space was great it was clean and in a small cool neighborhoodexquisite charming decor and spotlessly cleanclean spacious and central nice touchesHost:
david is a very nice hostdavid is a gracious and attentive hostpablo was a fantastic hostpablo was a fabulous hostvery good hostsRead more reviewsLocation:
great location with in walking distance of restaurantspablo’s place is really cute and super well locatedthe location is right in the heart of san francisco perfect and close to everythingcool place and great locationthe location was truly an oasis in the heart of the city
9. Casa Amador: Your home in Panama (from USD 77)
Casa Amador is an entire apartment that sleeps up to six guests in two bedrooms. Guests enjoy lovely views of the Panama Canal while being convenient to restaurants and shops. It is just five minutes from Casco Viejo which is famous for a vibrant nightlife. Albrook, just ten minutes away is good for shopping, and the unit is half an hour from the airport.
Your apartment comes with two balconies and two bathrooms. The kitchen is equipped so you can prepare your own meals. Television is provided for your entertainment. You can chill and relax as if you need someone to clean up and do your laundry, the hosts can arrange that. The building has a pool, gym, laundry, and 24 hr security. However, it’s on top a hill so you will need a car or use Uber.
Top guest reviews
Amenities & Room:
great view and cold a/cloved the views-the natural light that entered aptbeautiful apt with stunning viewthe amenities of the building are great and wifi was goodthere's air conditioning tvs and all the equipment is goodCleanliness:
the dishes weren’t very clean and there weren’t enough dishes/silverware for four peopleit was clean and quietmicrowave looked like it hadn’t been cleaned (food particles in it) shower could use a deep cleaningplace was clean and everything we wantedthe apartment was clean and as advertised in the picturesHost:
kent was verry helpful when whe contacted him by emailthanks kent you are a super hostkent was very understanding about the situation & is a gracious hostkent was responsive kind and very attentive to our needsthe host was extremely nice and helpful when we had any issuesRead more reviewsLocation:
we loved the locationgreat place & a great locationthe amador area is great location for familiesgreat lovely location and a very spacious placeoverall a great place and location
10. Entire house set in a tropical haven (from USD 278)
This entire house for rent in Panama City is located in a peaceful area in the city. It sleeps up to eight guests in four bedrooms. Up in the hills of Caceres, you will find birds, trees and beautiful gardens. It comes with cable TV, WiFi, a laptop-friendly workspace, a hair dryer, and a fully equipped kitchen.
There is a covered patio out the back and the kids will love the sparkling clean swimming pool. There’s a grocery store and a fresh produce stand close by for your essentials. Your host is friendly and able to advise you on places to see and attractions to visit. After a day out, relax in the hammocks and listen to the birds calling.
Top guest reviews
Amenities & Room:
the house has modern furnishings and provides a comfortable stayalso you can get fresh eggs from their chickens which come in very handy for breakfastthe breakfast was great and astrid and esilda were very kindwe really enjoyed the pool and sitting on the covered porch under the fantropical haven also has a great pool and if you like wildlife and flowers it's all thereCleanliness:
it was very clean and comfortablethe place was nice and cleanthe house was wonderful a comfortable and very clean place to relaxthe casita is beautiful very clean and fully stockedthe house was comfortable and clean and felt like a home away from homeHost:
the staff is very helpful and responsivesandra was a delightful hostsandra was an amazing hostsandra and her staff are exemplary and made us feel so welcomesandra was a great hostRead more reviewsLocation:
sandra's house is the perfect central locationthis place is a paradise oasisthe location of tropical haven is perfectthere is a nice grocery store close by that has everything you needwe had an amazing time at this location and i cannot recommend it highly enough
11. Luxurious property with an outdoor hot tub and pool (from USD 228)
Featuring so many greens as well as an outdoor swimming pool and a hot tub, this Airbnb vacation rental will surely make your holiday in Panama City one you can never forget. It is a lovely two-story house that has 3 bedrooms that can welcome as many as 16 guests, with so much space to roam around. Also, it comes with two living areas, a fireplace, a dining set-up, fully functional kitchen, a deck, a lookout bar, a garden, and more. Another great thing about this mansion is its location. It is in a secluded area in Chagres National Park, where you can go and see different species of birds and other wildlife.
Top guest reviews
Amenities & Room:
the views hit tub and pool were wonderfulwonderful house with an awesome view the view from the pool and hot tub is amazingspectacular views of panama city the canal and the jungle great pool and outdoor deckamazing pool and terrace and a complete house with everything that you might needthe view from the garden/pool is amazing one of the best i have seen so far in panamaCleanliness:
comfort safety space and it’s so cleanHost:
jonathan was very friendly and reacted quickly to all our questions and requestsjonathan was a fantastic host; he was very attentive kind and quick to respond to any questionsjonathan the host was wonderful attentive and informativethis place is magical and the host was superbbest host ever always great to stay at this placeRead more reviewsLocation:
gorgeous otherworldly location about an hour from panama cityif you like nature close to the city this is a place to gowe had an awesome time in a spectacular location
12. Private cottage in the heart of the city (from USD 85)
Located in a peaceful neighborhood in the heart of Panama City, this Airbnb vacation rental is a loft-style apartment that is surrounded by nature. The apartment can accommodate up to four guests with its one bedroom and a sofa bed. It comes with glass walls that make the place well-ventilated and lit. Also, it is complete with all the usual home features, such as a sitting area, dining area, and kitchen, as well as modern conveniences that include Apple TV, free Wi-Fi, and an airconditioning unit. Additionally, you’ll also find here a garden with outdoor furniture and barbecue facilities, which are perfect for entertaining guests.
Top guest reviews
Amenities & Room:
perfect a/c system all the kitchen utensils one needs to cook and very good internet connectionthe a/c was beautiful as the temperature outside was 90+ degrees and very humidthe only issue was that the wifi wasnt working =( besides that i will definitely stay againthey did both agreed that the couch bed was plenty comfortable for them during our stay herethe sleeping area was great too and the bathroom was decent with hot waterCleanliness:
the space was clean and as advertised in the pictureseverything was clean and comfortable with enough room for four peoplepablo's space was great it was clean and in a small cool neighborhoodexquisite charming decor and spotlessly cleanclean spacious and central nice touchesHost:
david is a very nice hostdavid is a gracious and attentive hostpablo was a fantastic hostpablo was a fabulous hostvery good hostsRead more reviewsLocation:
great location with in walking distance of restaurantspablo’s place is really cute and super well locatedthe location is right in the heart of san francisco perfect and close to everythingcool place and great locationthe location was truly an oasis in the heart of the city
13. Old town apartment (from USD 60)
What’s near: Natural Reserve Park
This large, one bedroom, ground floor apartment is the perfect choice for you if you’re looking for a stay in Panama’s Old Town (which is one of the most up and coming locations within Panama City). This charming apartment has been decorated with a colonial style, with a quirky, colourful twist added to the kitchen and the carpets. The apartment is supposed to fit four people, however one of the beds is a sofa bed so it would be more comfortable for just two. It’s the perfect place for two to hide out in the amazing Panama City.
Top guest reviews
Amenities & Room:
wi-fi also worked awesomegreat ac in both roomsair conditioning worked great in both the living room and bedroomthere’s good wifi a tv with movies etc good air conditioning and a cute little porchthe a/c in both rooms worked greatCleanliness:
apartment was clean however it had strong musty smellthe apartment is charming clean and comfortablethe apartment was clean had everything we needed and the beds were very comfortableursula provides fast communication and her apartment is at street level is stylish large and cleannice kitchen and open clean apartmentHost:
the host always responded to our questions in a timely and helpful manneroverall a great hostas a host she was communicative and helpful with recommendationsursula is a great host and very responsivei would definitely recommend ursula as a host and would stay again for sureRead more reviewsLocation:
its location is the bestgreat location and beautiful spaceamazing location close to many good restaurants and barsperfect location and comfy bednice place and great location : in the heart of casco viejo
14. Apartment with a view of downtown Panama (from USD 150)
What’s near: The Fish Market, only a two minute walk away
This stunning suite comes with what has to be one of the most beautiful views of downtown Panama City and the Pacific Ocean, from the bustling tourist destination of Casco Viejo. The apartment is unsuitable for those with walking difficulties as it is up on the third floor of an apartment, with no lift, unfortunately. However, once you do get up to the apartment it is large, comfortable and most importantly, clean.
You’ll be impressed by how close everything is to where you’ll be staying; all local shops, bars, cafes, even the famous Panama Canal are only a short walk away from your location in the beautiful Old Town.
Top guest reviews
Amenities & Room:
nice shower and acthe room is comfortable; the private rooftop provides a great view of the neighbourhoodthe rooftop view is so beautiful they let us do laundry which was wonderful air drying onlythe room is the master bedroom upstairs well appointed throughout private bath rooftop terrace for nice viewsour bedroom had all we needed to make our stay comfortableCleanliness:
everything was very clean and comfortablethe room and private bathroom are clean and spaciousthe place is super clean and has a comfortable bedthe apartment is modern clean and extremely comfortable especially the bedenjoy the clean and very stilysh decorated apartment and rely on alex tippsHost:
alexander was a really nice hostalexander was a great hostalexander was a great hostvery nice host very good timealex is a fantastic and accommodating hostRead more reviewsLocation:
great location in historic districtthe location was perfectgreat location as wellgreat location just minutes walk to casco viejogood location good value
15. Funky oceanfront apartment
What’s near: Plaza Simon Bolivar
If I said to you to book this apartment and to do it right now, I wouldn’t be over-dramatic. This absolutely stunning one bed / one sofa bed, oceanfront apartment is the perfect place to impress your travel buddies. From the funky decor with its colourful walls to the stunning views, everything about this apartment is designed to leave you speechless. The rooftop pool has got to be one of the most lavish in Panama with views that are unrivaled.
Panamá, Panama
30.46 km (19.0 mi) from Romeo y JulietaAccommodates: 4
Top guest reviews
Amenities & Room:
apartment was as described and view was gorgeousvery lovely spacious apartment with a fantastic view and comfortable bedthe view is beautiful and it was nice to relax at the swimming poolvery comfortable and modern stay and great amenitiesapartment is well equipped nice pool area to chill - good gym for a workout with amazing viewsCleanliness:
and more clean linens made availablethe place is clean safe and very comfortableit was clean as heck and conveniently locatedHost:
amazing place with a fantastic hostshe responded within minutes to all of our questions and was very helpfulshe has documentation on places to eat and visit which was very helpfulursula the host is an incredible wealth of knowledge for places to visit eat dance etcursula is very helpful and answers super fastRead more reviewsLocation:
great experience really good locationgreat location everything was super walkable or easy to get an uber/taxi fromthe place is very central in panama city which makes getting around super easyit’s a great way to see the city and the bike path is across the streetthis is a great place to stay in panama city
16. Apartment in the heart of the banking district
What’s near: Banking and Business District
Do you want an apartment that’s right in the very heart of Panama City’s banking district? With bonus points for undisrupted views of the sea and sky? Of course you do. This simple, but beautiful apartment would be the perfect choice for you. This classic but comfortable condo has city and sea views over downtown and the Pacific Ocean - the perfect place to lay back by the rooftop pool after a busy day exploring central Panama City.
17. Historic one bedroom apartment
What’s near: Tantalo Roofbar, for drinks and Tapas with an amazing view of downtown Panama City
Stay in a historic apartment in one of the most thriving suburbs of Panama City; Casa Viejo. This stunning one bedroom apartment is perfect for someone travelling alone or as a couple. It comes with a comfortable bedroom and a fully equipped kitchen that is bothn a living and dining space.
What will grab you about this apartment is the modern interior, perfectly matching the hip Casa Viejo, which is thriving with cosy cafes, amazing restaurants, secret bars and clubs. You won’t be short of things to do when staying in this gorgeous apartment.
Panama City, Panama, Panama
31.87 km (19.9 mi) from Romeo y JulietaAccommodates: 2
Top guest reviews
Amenities & Room:
wifi and ac reliable nice buildingwe had no issues with the wifi and the ac worked greatgood ac in both the living room and bedroomthe apartment is light on amenities so a certain amount of self-sufficiency is requirednice apartment liked the place and the patio was a nice touchCleanliness:
very clean and nicely furnishedquite clean and safeother than that the flat was clean and bed was super comfythe apartment was incredible so clean and beautifully decoratedclean safe and quiet -- it offered everything i was looking forHost:
viocary is a great hostthe host was great helped me to carry my suitcase up and answered my questions quicklythe studio had all we needed communication with the owner was efficient as was getting the keyscommunication with the owner was clear and easya wonderful place in a wonderful location our host was very accommodating and thoughtfulRead more reviewsLocation:
the location is excellentloved the location of this aptbest location in casco viejowonderful location chic designnice place great location
Welcome to Panama City!
Whether you’re travelling for business or pleasure and wondering where to stay in beautiful Panama City in Central America, we’ve listed the top Airbnb rentals. Panama City is a colourful, exciting place to explore and you’ll have the time of your life. We hope you love it as much as we do.
Frequently asked questions about Airbnb vacation rentals in Panama City, Panama
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