Top 10 Luxury Airbnb In St. Louis, Missouri - Updated 2022


Situated along the Mississippi River, St. Louis is a popular destination that you wouldn’t want to miss when having a vacation in Missouri. Admire the city’s most popular landmark, Gateway Arch, which was built in the 1960s to commemorate the massive expansion in the west. You can please your eyes with idyllic views of colorful flowers and plants at Missouri Botanical Garden. Stop by Saint Louis Zoo to meet its adorable inhabitants such as penguins and large mammals. There are also a number of hotels with rooftop pools and kid-friendly hotels where you can stay. For a more memorable vacation experience, you can choose the accommodation that can provide you with modern comforts. Keep reading to see the top luxury Airbnb in St. Louis, Missouri.

1. Elegant mansion with a private backyard (from USD 300)

This elegant mansion is spacious enough for eight guests. With four bedrooms, guests can surely enjoy a good night’s sleep. Set on a quiet street, the house promises a peaceful escape away from the stressful city. When you want to unwind, you can go to the private backyard and indulge in a good wine. There is a large kitchen where you can prepare a delicious meal to be enjoyed in one of the two spacious dining rooms.

Elegant and Luxurious Mansion on a Quiet Street
St. Louis, Missouri, United States
40 reviews  Wifi Available
Entire home 4 Beds 8 Guests 4 Bedrooms 4 Bathrooms

Accommodates: 8

Top guest reviews
Amenities & Room:
furniture was comfortable and contemporary
fabulous french country kitchen equipped with everything
perfect for our family of 7 with lots of room to spare
the kitchen was well stocked closets/drawers very organized and house was very clean
very clean and spacious
we left the house exceptionally clean
very clean and spacious for a larger number of guests
it is stylish homey and clean
the kitchen and bathrooms were well-stocked and clean
the hosts were responsive to our questions
owner and his manager very responsive
make sure to give your uber driver the instructions the host provides
surprised to find real tea michele is very easy to communicate nice host
michele was an amazing host quick to respond and went above and beyond our needs
the location was great
great central west end location on a private and quiet street
the location was near the park and downtown and easy access to the highways
in a great neighborhood and in a great location in the city
beautiful house in a beautiful location in a beautiful city
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2. Five-bedroom home with modern amenities (from USD 409)

Have a pleasant stay at this remarkably preserved Craftsman house that boasts an intact exterior character. Guests can stay connected as the place offers free WiFi access. The chef’s kitchen with complete cooking appliances can help you prepare your meals with ease. A formal dining area can help you relax and enjoy your meal. If you prefer to have outdoor dining, you are welcome to use the outdoor dining table. Featuring five bedrooms and four bathrooms, the house is great for ten people.

Updated Period Family House Across From Tower Grove Park
St. Louis, Missouri, United States
132 reviews Superhost  Wifi Available
Entire home 5 Beds 10 Guests 5 Bedrooms 4 Bathrooms

Accommodates: 10

Top guest reviews
Amenities & Room:
beds were comfortable and amenities were more than expected local restaurant guide snacks
plenty of bathrooms and space to play they even had some toys and high chairs stored upstairs
loved that the bedrooms had ceiling fans and ac was great for muggy days
tv and multiple living rooms worked well for different groups hockey fans vs hgtv haha
the house was very comfortable and had everything we needed
beautiful impeccably decorated and spotlessly clean location
the house was exceptionally clean and well laid out
very spacious clean up to date house
the house is nicely decorated and sparkling clean
the place was very nice and spacious very clean and perfect for me and my family
the owner was incredibly nice
hosts were kind and personable
working with the host was very easy
and they were very helpful with accommodating our late checkout
dave is a gracious host and is very accommodating and easy to communicate with
excellent location and beautiful home
it is close to beautiful tower grove park and centrally located to st
perfectly situated near the park and walking distance from so much
the neighborhood is very nice and the location is great
the location is fantastic lots of restaurants nearby and downtown is 15 minutes away
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3. Contemporary apartment with an indoor fireplace (from USD 375)

Situated near Forest Park and Saint Louis Zoo, this luxurious Airbnb vacation rental features two spacious bedrooms. In each of the bedrooms, you can find a king bed and a large-screen Smart TV to keep you company before you go to sleep. In the morning, you can relax over a cup of coffee in the living area that has its own Smart television. There is also a cozy outdoor area where you can breathe in the peaceful atmosphere and enjoy the view of the surroundings.

Extraordinary luxury CWE 2BD/2BH 2F
St. Louis, Missouri, United States
18 reviews  Wifi Available
Entire home 2 Beds 6 Guests 2 Bedrooms 2 Bathrooms

Accommodates: 6

Top guest reviews
hui place is top notch very clean modern and comfee grocery stores are near by
mei was a super host any questions or issues her response was within minutes
this place was well worth the money
nightlife is blocks away perfect location
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4. Charming house with custom lights and sounds (from USD 324)

This pet-friendly Airbnb has three bedrooms that can comfortably accommodate 10 guests plus pets. It boasts custom lights and sounds. During the day, you can snuggle up on the posh sofa in the living room and turn on the television. The luxurious rental is equipped with two modern bathrooms for the guests’ convenience. You won’t have to worry about staying connected as the place comes with free WiFi access throughout your stay.

Modern Luxury 3-Story New STL Home
38 reviews Superhost  Wifi Available
Entire townhouse 4 Beds 10 Guests 3 Bedrooms 2 Bathrooms

Accommodates: 10

Top guest reviews
awesome stay very clean host was great highly recommend
clean and very modern to include numerous lighting options gormet kitchen decks private garage and pool table
the host was very helpful and responded quickly to my questions
great host very good at communicating
the host are really nice and very responsive and accommodating great stay
host communicates well and provides helpful information
not to forget to mention the beds are so comfortable this place makes you feel like queen
great place to stay in st
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5. Cozy and bright house for 12 guests (from USD 332)

Enjoy a luxurious stay at this cozy and bright vacation rental located near downtown St. Louis. The house’s master bedroom features a queen bed and a master bath. You can prepare a home-cooked dinner in the kitchen that comes with cooking necessities and a coffee maker. In the evening, cozy up by the fireplace before you enjoy your favorite movie on the Smart TV with complimentary cable programs.

Beautiful, Modern & Spacious. 5BDR Sleep 10
St. Louis, Missouri, United States
77 reviews Superhost  Wifi Available
Entire home 6 Beds 12 Guests 5 Bedrooms 3 Bathrooms

Accommodates: 12

Top guest reviews
Amenities & Room:
the kitchen had a fun snack bar with cute chairs as well as a large table for meals
we enjoyed having tv access on all 3 levels
beds are comfortable water is hot and the space is ample and gorgeous
very clean and accommodating
it was very clean and comfortable
everything was new clean and updated
very clean and a great layout
very clean convenient location great communication would definitely stay again
she was a wonderful host with a beautiful place
remi is a great host ultra responsive
remi was a great host
this house was beautiful and the host was great
you can expect a very attentive and responsive owner
we loved the location
it was so close to the attractions we wanted to see
i would recommend this location for any large group trip
we were in town for a concert at the enterprise center so this location was perfect
with a great location great amenities and centrally located place
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6. Luxurious penthouse with WiFi (from USD 393)

Experience a fantastic stay at this heavenly penthouse that is only a few steps away from The Fountain on Locust and Center Ice. You can enjoy a restful sleep in one of the two massive bedrooms that boast king beds and premium linens. Recharge in the airy living room that features plenty of windows to bring in natural light. In the kitchen, you can use top-of-the-line appliances such as a massive gas cooktop and a wine chiller to prepare a nice dinner.

The Aviators Penthouse Loft- Bridal Suite & More!
St. Louis, Missouri, United States
136 reviews Superhost  Wifi Available
Entire condo 3 Beds 10 Guests 2 Bedrooms 2 Bathrooms

Accommodates: 10

Top guest reviews
Amenities & Room:
the furniture was gorgeous and comfortable
comfortable furniture to help you relax
the living room couch was so comfortable we all fell asleep on it watching tv
the bed is like sleeping on a cloud
the decor is top notch and the furniture is super comfortable
the property was very clean
rooms and beds were sparkling clean
the house was clean
they do an extremely good job of keeping the rooms/bathrooms clean - everything was spotless on check-in
the shower and jetted bathtub were amazing it was a gorgeous clean and spacious place
the host was very responsive
the host was wonderful and very prompt with responses
great response time from the host and lots of wonderful touches
joshua was a wonderful host
the host was quick to respond and very helpful
the location is also excellent
great place to stay near downtown st
awesome space and close to everything
great location with grown and sexy vibe
the location was great and the kitchen was amazing
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7. Stylish house with a rooftop patio (from USD 358)

Enjoy a memorable stay with your loved ones by staying at this stylish house that is ideal for 12 people. The house comes with five bedrooms and four bathrooms and is located just a few minutes away from the downtown area. The best feature of the house is perhaps its rooftop patio, where you can take in the beauty of the famous Gateway Arch while you drink your favorite cocktail. You can also enjoy whipping up a delicious lunch in the kitchen that features an electric fireplace.

Luxurious & Modern 5BDR. Rooftop deck w/ Arch view
St. Louis, Missouri, United States
133 reviews Superhost  Wifi Available
Entire home 6 Beds 12 Guests 5 Bedrooms 4 Bathrooms

Accommodates: 12

Top guest reviews
Amenities & Room:
4 floor more like sitting room and outside balcony view
the house is impeccable comfortable with all the necessary amenities
plenty of room for our family of 7 and a friend
space on main level for activities and plenty of room to visit with friends and family
clean and comfy
very beautiful and clean
very clean and stylish love this place
super big and absolutely clean
the house was clean remodeled nice
she was a great host
great host with a great home
remi was a wonderful host
the owner is very responsive and easy to work with
remi was a very gracious host
the location was great as well
it’s location is minutes from everything and great restaurants near by
nice place nice location; convenient for our trip to the arch and the old court house
perfect location for baseball the arch botanical gardens and many other places
loved the location and the pictures don't give this place justice i will return
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8. Large house with a patio (from USD 500)

Comprising two roomy units, this duplex offers a comfortable stay for up to thirteen travelers. Three large televisions and a collection of DVDs are available to keep every guest entertained. Whether you are staying with your kids or a group of friends, you can have fun playing board games in the spacious living room. You can also head to the large backyard that comes with a patio. Here, you can enjoy the porch swing or indulge in a delectable dinner at the patio dining table.

Group-Friendly Duplex – 5 BR, Great for 2 families
St. Louis, Missouri, United States
7 reviews  Wifi Available
Entire home 7 Beds 12 Guests 5 Bedrooms 2 Bathrooms

Accommodates: 12

Top guest reviews
Amenities & Room:
comfy beds and good communal space
it also very comfortably fit our group of 10 with more than enough room for everyone
location is excellent for close proximity to attractions and family events
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9. Comfortable house with a generous living room (from USD 250)

Unwind and recharge at this comfortable house that welcomes up to 15 guests. You can find a spacious bedroom on the ground floor. Situated near the bedroom is a bathroom where you can see a sleek walk-in shower and an elegant vanity area. The four other bedrooms are located upstairs. To relax, you can chill in the living room that comes with two lovely armchairs, large windows for plenty of sunlight, and decorative light fixtures, among others. The kitchen is equipped with stainless steel appliances and transitions into a formal area for dining.

Spacious & Stylish 5BR Home|Tower Grove Park|1st Fl Bed & Full Bath //ABODEbucks
St. Louis, Missouri, United States
109 reviews  Wifi Available
Entire home 10 Beds 15 Guests 5 Bedrooms 3 Bathrooms

Accommodates: 15

Top guest reviews
Amenities & Room:
i loved all the natural light in the bedroom and living room
the blankets were soooo comfortable and we had everything we needed
these guys are fantastic a great location wonderful amenities and so incredibly comfortable
the beds were comfortable and we had enough appliances to prepare breakfast and lunch
the kitchen and dinning room tables were the perfect spot to gather eat drink and spend time
the place was clean and spacious
fantastic clean open floor plan
very nice place very clean and modern
clean lots of beds lots of space
rooms are spacious comfy beds and very clean
our hosts were very helpful
the host understands exactly how to make his guests feel welcomed
terrance is the most thoughtful gracious host
terrence is such an awesome host
the host was quick to respond welcoming and had suggestions for the area
the location is pretty central to most things
great location right across from park
close to major attractions in downtown area
great location also about a 8 minute uber ride to busch stadium
convenient location and having the park right across the street is added bonus
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10. Century-old house with a luxurious bath

Set in a quiet location that is close to the downtown area, this century-old house can charm you with its gorgeous interior. You can admire the view of Compton Hill Reservoir Park that is situated in front of the house. It comes with three bedrooms and three-and-a-half bathrooms and can accommodate up to eight people. Whenever you feel like relaxing, you can soak in the luxurious master bathtub. The decorative fireplaces can add to the rental’s beauty and coziness. There is also a kitchen equipped with a stove and cooking basics to help you cook some delicious family meals.

Gorgeous century-old updated home near downtown
St. Louis, Missouri, United States
32 reviews
Entire house 4 Beds 3 Bedrooms 3 Bathrooms
Top guest reviews
Amenities & Room:
the piano is a fantastic touch and the kitchen is gorgeous
fast wifi great location highly recommend
we had plenty of room for everyone and it was a great backdrop for photos
definitely shower in the master it will be magical richard is very responsive and helpful with any concerns
very clean communication was excellent big house with lots of space very safe neighborhood and quite would stay again
richard's home is very clean spacious and beautiful
beautiful spacious and cozy very unique place with lots of local charm
beautiful house and the host was so accommodating
he was so very attentive and helpful
richard was an amazing host
the host is also super responsive and great i hope to stay again in the future
great central location that made getting around town a breeze
great house neighborhood and general location in st louis
very nice master bathroom and convenient location that feels safe
a great location close to everything accommodating with check in and check out times
fantastic location very nice accommodations wonderful host
Read more reviews

Experience luxury in St. Louis

St. Louis offers picturesque scenery and numerous tourist attractions that visitors wouldn’t want to miss. Book one of the top luxury Airbnb in St. Louis, Missouri, and enjoy a grand vacation.

If you’re up for more adventures, take some of the best day trips or road trips from St. Louis, Missouri.

Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.

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