The quaint town of Santee offers a delightful mix of natural beauty and Southern charm. It’s a great destination for golfing enthusiasts, with golf courses such as Santee National Golf Club and Lake Marion Golf Course. Nature lovers can visit the nearby Santee National Wildlife Refuge or take a stroll along the lovely Lake Marion.
If you are planning a trip with your pet, you’ll be delighted to find parks where you and your dog can enjoy strolls and outdoor activities together. Some popular options include Santee State Park, where you can hike scenic trails and relax by the lake. You may also take your fur babies to The Canine Country Club for a grooming session! Additionally, several restaurants have outdoor seating areas that allow dogs, ensuring you can savour a meal with your furry friend.
For a hassle-free stay with your pet, here’s a list of the top pet-friendly hotels in Santee, South Carolina.
We handpicked these listings carefully, considering (wherever possible) recent guest reviews, location, accommodation type, prices, availability of dates, decor, and pet-friendly rules and regulations. The image galleries get refreshed with the latest updates regularly. They were last updated on October 28, 2025.
1. Best Western PLUS Santee Inn (from USD 169)
Boasting clean and comfortable rooms, Best Western PLUS Santee Inn is a perfect choice of accommodation for you and your pet.
The 3-star hotel has complimentary wireless internet to keep you connected and comes with air-conditioned rooms. Take a refreshing dip in the outdoor heated pool to unwind. Every room also comes with a flat-screen TV for your entertainment. You can start your day with a delectable American breakfast served at the hotel before heading out. There are also vending machines stocked with snacks and beverages.
The property also accepts your four-legged companions for an additional fee. For any inquiries regarding the accommodation of pets, please do not hesitate to contact the hotel directly.
Best Western PLUS Santee Inn
Address: 9059 Old Number Six Highway
4.06 km (2.6 mi) from Santee State Park
2. Fairfield Inn & Suites by Marriott Santee (from USD 158)
Fairfield Inn & Suites by Marriott Santee comes with expansive spaces to walk your pet, a stunning outdoor patio with a fire pit, a complimentary buffet breakfast, and more to keep you satisfied. You will also find reliable WiFi to help you stay connected.
The hotel allows dogs and cats for a non-refundable charge of 50 USD per night. Service animals are exempt from fees. According to the Marriotts Pet Acceptance Programme, which you have to sign during check-in, the pet should not weigh more than 40 pounds (18.14 kilograms). Moreover, only one pet per room is allowed.
Nearby pet-friendly restaurants include Santee Canteen and Santee seafood bistro. After a hearty meal, you can take your pet to Santee State Park for a walk.
Fairfield Inn & Suites by Marriott Santee
Address: 9074 Old Number Six Hwy
4.43 km (2.8 mi) from Santee State Park
3. Hampton Inn Santee-I-95 (from USD 163)
Experience a comfortable stay at Hampton Inn Santee I-95. Enjoy an ideal location within walking distance of restaurants and the beautiful Lake Marion Golf Course. The hotel welcomes a maximum of two pets (dogs and cats) at 50 USD per room. For five or more nights, the pet fee is 125 USD.
Start your day with a complimentary hot breakfast to feel energised before heading out to explore the natural wonders of Lake Marion and Santee National Wildlife Refuge, just 5 miles (8.05 kilometres) away. You can also take a short drive to Santee State Park to hike on scenic trails with your fur baby.
Alternatively, you can unwind in the hotel’s outdoor swimming pool, keep up with your fitness routine in the well-equipped gym, or take care of business needs in the 24-hour business centre.
Hampton Inn Santee-I-95
Address: 9060 Old Number Six Hwy
4.39 km (2.8 mi) from Santee State Park
4. Baymont by Wyndham Santee (from USD 88)
Located in the city centre, Baymont by Wyndham Santee welcomes you to a comfortable stay close to golf courses, nature parks, and restaurants. Guests can check in with a dog or cat at an additional 15 USD. There is no charge for service animals. You can spend quality time with your furry companion at nearby pet-friendly tourist places such as Santee State Park and Santee National Wildlife Refuge.
The hotel offers free continental breakfast and covers all modern amenities such as WiFi, concierge services and a 24/7 front desk. If you are on a road trip in an RV or bus, the hotel comes with free parking for big vehicles.
Baymont by Wyndham Santee
Address: 249 Britain Street
4.05 km (2.6 mi) from Santee State Park
5. Holiday Inn Santee, an IHG Hotel (from USD 128)
Looking for a getaway with a combination of outdoor activities and relaxation? Look no further than Holiday Inn Santee Hotel, an IHG Hotel. The property’s location makes it convenient for guests to take a day trip to Columbia or Charleston.
For recreational activities, you can take a quick drive to Santee National Golf Club. If fishing makes you happy, head to Lake Marion to catch some striped bass and catfish. You also have the option of visiting the beautiful Edisto Memorial Gardens with your furry friend. After an eventful day, indulge in comfort food at the hotel’s restaurant and rejuvenate in the pool.
Dogs and cats that weigh 45 pounds (20.41 kilograms) or less are welcome at the hotel at a charge of 30 USD. The fee increases to 60 USD if your fur baby weighs 50 pounds (22.68 kilograms). Service animals are exempt from fees.
Holiday Inn Santee by IHG
Address: 139 Bradford Blvd
3.92 km (2.5 mi) from Santee State Park
A 'pawfect' getaway with your fur babies
As a fur parent, it is not easy to leave your pets behind. It can also be tricky to bring them along as not all locations or accommodations are pet-friendly. However, if you’re travelling to Santee and want to bring your fur babies along, rest assured that the town will welcome you with open arms. You can easily book any of the above-listed options and have a great stay!
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