Inhabiting the western bank of the Mississippi River in USA’s Missouri state is the city of St Louis, also known as the Gateway City to the country’s west. It is most famous for the Gateway Arch, a monumental arched, steel structure resembling a gate, metaphoric of the city’s significance and geographical position. Also a thriving inland port, St Louis has strongholds in cultural, historical, religious, and political roots, making it an independent and metropolitan city. It attracts many thousands of tourists each year and making their stay even more special are the numerous things to do in the city. It also has its fair share of amazing accommodation options, such as kid-friendly hotels, if you’ll bring your family in your trip. But for a unique stay, consider checking out this list of the best themed hotels in St. Louis, Missouri.
We handpicked these listings carefully, considering (wherever possible) Superhost status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on April 19, 2025.
1. The Royal Sonesta Chase Park Plaza St. Louis (from USD 240)
With refined decor, each of the rooms at The Royal Sonesta Chase Park Plaza St. Louis gives a charming and modern appeal to its guests. The lobby and bar both exhibit a blue motif, evoking a cool ambience. Its rooms also have white and mint green accents that give off a spacious vibe.
Inside the room, you can take advantage of its desk and chair if you need to work remotely. It also has a flat-screen TV and WiFi for entertainment. You can also try the savoury dishes served by The Tenderloin Room, the restaurant on site. If you’ll bring your four-legged friends during your stay, a maximum of 2 pets are allowed at an additional charge of 80 USD per pet.
The Royal Sonesta Chase Park Plaza St Louis
859 meters (0.6 ft) from Cathedral Basilica of Saint Louis
2. Angad Arts Hotel (from USD 187)
Are you one who likes art in every aspect of their everyday life? Here’s one art-themed hotel that’ll satisfy the artist in you to the very core. Located 6 km (3.7 miles) from the famous Gateway Arch is this five-star hotel, whose sumptuously painted rooms are a stunning picture of expressiveness in the form of colours. The rooms here are not only a practical delight, but also poetic in their tasteful decoration. What’s even more unique about this hotel is that you not only get to choose your desired room on the basis of price and amenities, but also colour scheme! Each room has been painted in a different colour, with the aim of letting their guests select what colour suits their emotion best! After all, different strokes for different folks, right?
Angad Arts Hotel St Louis, Tapestry Collection by Hilton
2.15 km (1.4 mi) from Cathedral Basilica of Saint Louis
3. St. Louis Union Station Hotel, Curio Collection by Hilton (from USD 278)
Great dining experiences with fresh and perfect food. Breakfast buffet, but limited late dining options. Pricey breakfast and no free continental breakfast.
Reasonable parking at $5 a night with Aquarium discount. Room pricing higher than expected.
Convenient location with walking access to attractions, but limited dining options nearby. Easy access to Union Station activities.
Historic architecture, restaurants, bars, and connected attractions like the aquarium and Ferris wheel. Some accessibility challenges for disabled guests.
If you’re looking for unique places to stay in St. Louis, this hotel in the city’s downtown lends its inspiration to 19th-century architecture. The Gothic Revival-lookalike tower outside will capture your breath. However, slide indoors and you’ll find yourself marvelling underneath colourful frescoes coming to life with gold-leaf detailing, accentuated by vibrant mosaics in their main lobby. Move in further, and you’ll find each room here spacious and carefully designed, in sync with the landmark status of the hotel.
Opt for the suites and you’ll even get an attached courtyard and exclusive lounge access. Housing underneath its elegant limestone facade are rooms and facilities that’ll transport you into a bygone era and fill you with utter awe, so head here for a fully luxurious experience.
St. Louis Union Station Hotel, Curio Collection by Hilton
4.38 km (2.8 mi) from Cathedral Basilica of Saint Louis
4. Magnolia Hotel St. Louis (from USD 200)
Good on-site restaurant, but breakfast may not be included in the price.
Varied pricing, but parking and breakfast may incur additional costs.
Convenient downtown location near attractions, but parking options are limited and pricey.
Historic charm, spacious rooms, beautiful lobby, and friendly staff.
A beacon of sophistication and unparalleled hospitality, this erstwhile Mayfair Hotels’ property was recently renovated and opened under its current name. Emanating splendour are the crystal chandeliers that adorn several parts of the hotel, with stained-glass windows adding every bit of gorgeousness to the feel. Spread across an area of 371 square m (4,000 square ft), the hotel’s grand ballroom is quite possibly the crowning jewel of the property.
As for its accommodation, there’s not much you’ll find lacking. If you’re looking for themed hotel rooms for adults in St. Louis, its suites are perfect for you since they are distinctly modern and utterly comfortable. There’s something wholly fulfilling about entering your hotel room and finding an exquisitely-wrapped piece of chocolatey goodness proudly sitting on the pillows, right? Legend has it that here’s where that tradition started!
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel This is a Proud Certified property where you can be extra sure of a welcoming stay.
5.64 km (3.6 mi) from Cathedral Basilica of Saint Louis
St. Louis Tour Guide
Melissa Smith
I began my guiding career as a teenager in St. Louis, where I was born and raised. I first volunteered as a guide for the Chatillon-Demenil Mansion in South St. Louis. There is where I fell in love with history and its effect on present day. From my teenage years as a volunteer, I progressed to a job at the Missouri Botanical Garden where I trained and supervised the School Program Volunteer Do... Read more
Tours by Melissa
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5. The Moonrise Hotel (from USD 201)
Attached restaurant Eclipse and nearby dining options provide diverse culinary experiences.
Reasonably priced for the area, with free parking.
Conveniently located in the vibrant Delmar Loop area, near attractions and restaurants.
Unique moon-themed decor, rooftop bar, and electric vehicle charging.
Looking for fantasy suites in St. Louis? Strewn with toys, decorative items, and art, you’ll find The Moonrise Hotel a unique homage to all things astronomy. Their iridescent walls and incandescent staircases lead you into their quirkily designed rooms and suites, also following the same theme. Head over to their on-site restaurant, Eclipse, to enjoy some American cuisine.
Just like Laika, Belka, Strelka, and Félicette made a trip beyond Earth, bring your little friend to this faux-Space in St Louis. The Moonrise Hotel has an entire floor of rooms dedicated to pet parents and many a perk for your little buddies! The hotel is also quite heavily into eco-conscious alternatives and choices.
Moonrise Hotel
4.1 km (2.6 mi) from Cathedral Basilica of Saint Louis
6. The Cheshire (from USD 191)
Experience a bit of Britain in St Louis at this hotel, styled like a traditional British inn, built in Tudor-style architecture. The amazing experience begins even before you enter the premises, with a striking red British telephone booth placed outside. As you move indoors, the stately hand-carved mantle and stained-glass windows across the hotel will leave you awestruck. Above and beyond the spectacular common areas, you’ll find that the rooms are equally stunning. Their decoration is done up as a tribute to famous British literary figures, such as Charles Dickens, Jane Austen, and William Shakespeare, with elegant paintings and antique show pieces. While you’re still soaking in the British decor elsewhere, step into their in-house restaurant, Fox & Hounds, and enjoy some British fare too. The plushness of The Cheshire will leave you beaming with a cheshire cat-like smile as you checkout.
The Cheshire This is a Proud Certified property where you can be extra sure of a welcoming stay.
4.64 km (2.9 mi) from Cathedral Basilica of Saint Louis
7. The Last Hotel (from USD 146)
Reward yourself with a relaxing stay at The Last Hotel, a luxurious accommodation that has two bars and a 24-hour gym. This boutique hotel has an Art Deco style, as exhibited by its stone carvings blended with fancy metalwork to give off architectural grandeur and modern appeal. Its rooms also feature a barrel-vaulted ceiling to emphasize its airy ambience.
Each of its suites offers plush linens, a king-sized bed, a minibar, and a walk-in shower. The hotel has an outdoor pool if you want to swim some lapses and unwind. If you have a car, you can also use its private parking space for a 30 USD fee per night.
The Last Hotel
Address: 1501 Washington Ave
4.84 km (3.1 mi) from Cathedral Basilica of Saint Louis
A novel affair
While in St Louis, there’s quite a bit you can pack your schedules with – a tour of the Gateway Arch and museum, City Museum, Missouri Botanical Garden, or Laumeier Sculpture Park among several other tourist-friendly places. If you’re one who enjoys exploring cities on foot, The Hill is the one of the city’s most popular and colourful neighbourhoods. Once done, you can head to the Delmar Loop for a great evening. Not only does the city make a trip great, but also where you choose to stay. So, add dollops of special to your trip to St Louis by staying at these themed hotels. We guarantee you’ll return with a bag full of beautiful memories.
Frequently asked questions about themed hotels in St. Louis, Missouri
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