San Francisco is one of America’s most iconic cities. Spread over a series of rolling hills overlooking a bright blue bay, it seems impossible that the city’s neat rows of houses were ever constructed. The city boasts many famous buildings, but there is much more to it than just its postcard-perfect scenery. Foodies should head to the Mission District for authentic taquerias or Chinatown to browse the dozens of food markets. History buffs will get a thrill from taking the ferry to Alcatraz to learn about the island’s fame as an inescapable prison. There is something for everyone in the city by the bay, and you could spend a lifetime experiencing it all. Read on for our list of the best two-bedroom hotels in San Francisco, California.
We handpicked these listings carefully, considering (wherever possible) recent guest reviews, location, accommodation type, prices, availability of dates, decor, and access to two bedrooms. The image galleries get refreshed with the latest updates regularly. They were last updated on October 28, 2025.
1. The Suites at Fisherman's Wharf
The Suites at Fisherman’s Wharf offers spacious rooms right in the heart of the city’s most popular area. Also, this 3-star hotel features two-bedroom suites in San Francisco that all have kitchenette facilities and dining areas. Some of the rooms have balconies overlooking the nearby cable car route, and there is also a roof deck where all guests can catch gorgeous views of the bay.
All of the shops and attractions of Fisherman’s Wharf and Ghirardelli Square are just steps away. Spend more of your time exploring and less time commuting around town by staying at this hotel.
The Suites at Fisherman's Wharf
Address: 2655 Hyde Street
2.27 km (1.5 mi) from Union Square
2. Hilton San Francisco Union Square (from USD 518)
With great amenities and an amazing location in Union Square, this hotel offers the perfect balance between relaxation and adventure. During your downtime, you can choose from swimming in the courtyard pool, working out at the fitness center, or soaking in the hot tub. There are several restaurants and a lounge right on site, where you can end your day or start your evening adventures.
The double-room hotel in San Francisco features two-bedroom suites which include a parlor. The suites sleep up to 12 guests, making them ideal for a family or several couples traveling together.
Hilton San Francisco Union Square This is a Proud Certified property where you can be extra sure of a welcoming stay.
Address: 333 O'Farrell Street
361 meters (0.3 ft) from Union Square
3. Club Wyndham Canterbury
Another great hotel option near Union Square is Club Wyndham Canterbury. This boutique-style hotel has a gorgeous lobby with luxurious furnishings which you will also find in the rooms. Club Wyndham Canterbury offers two-bedroom suites with two queen beds and one sofa bed to ensure a comfortable night’s sleep. All suites also have cable TV, free wifi, and a bathtub in the bathroom for ultimate relaxation. Visit the hotel’s game room during your downtime to play arcade games or billiards.
Club Wyndham Canterbury
Address: 750 Sutter Street
466 meters (0.3 ft) from Union Square
4. Cow Hollow Inn and Suites (from USD 184)
Cow Hollow Inn and Suites provides luxurious suites with a home-away-from-home vibe. Select a two-bedroom suite to take advantage of the kitchen facilities and curl up by the cozy fireplace in the living area. The hotel has other amenities like a 24-hour front desk as well as free parking if you’re traveling by car.
If you are flying in but aren’t renting a car during your stay, the hotel offers a free airport shuttle so you can easily make your flight. Right outside your door are the lovely Marina District and lots of restaurants and shopping options.
Cow Hollow Inn and Suites This is a Proud Certified property where you can be extra sure of a welcoming stay.
Address: 2190 Lombard Street
2.95 km (1.9 mi) from Union Square
5. The Fairmont Heritage Place Ghirardelli Square (from USD 957)
The Fairmont Heritage Place Ghirardelli Square is housed in a former chocolate factory that was built in 1893. The interior has been redesigned to retain the industrial feel with exposed brick walls in each room, while the elegant furnishings create a relaxing atmosphere. The entire 5-star hotel consists of apartment-style rooms, such as two-bedroom units with fully equipped kitchens. If you don’t feel like cooking, you can avail yourself of room service from one of the hotel’s two on-site restaurants.
Fairmont Heritage Place, Ghirardelli Square
Address: 900 N Point Street
2.34 km (1.5 mi) from Union Square
6. Nob Hill Inn (from USD 345)
Nob Hill Inn is a beautiful historic hotel located in one of San Francisco’s famed Victorian homes. The 1907 building was once a private residence and it still feels homey.
Inside, the hotel’s unique decor gives the place character you won’t find anywhere else. Select a two-bedroom unit if you are staying with your family. The hotel is in an excellent location—a short walk from San Francisco’s famed Chinatown, where you can find an array of restaurants and interesting stores to browse.
Nob Hill Inn
Address: 1000 Pine Street
536 meters (0.4 ft) from Union Square
7. Fairmont San Francisco (from USD 454)
Enjoy a pleasant stay at this luxurious hotel downtown. Energize yourself with a workout in the gym or a steaming cup of coffee in the on-site cafe. There are two on-site restaurants to satisfy your culinary needs and two in-house bars for a nightcap. The hotel also features a full-service spa, allowing you to leave destress from your busy life.
Moreover, there are 606 elegant suites in the hotel, and the Napoleon Suite boasts two bedrooms with stunning city views. You will find one king bed, two queen beds, and one double sofa bed in the room, promising utmost comfort to all.
Fairmont San Francisco
Address: 950 Mason Street
567 meters (0.4 ft) from Union Square
Stay in style in San Francisco
Featuring shopping malls and amazing tours, San Francisco offers so much to see and do that you will want your hotel to be extra comfortable. The two-bedroom hotels on this list offer plenty of space to relax and unwind in between the day’s exploration and the night’s adventures. Select a hotel that fits your price point and the neighborhood you’d most like to stay in, and you will be halfway to your dream trip to San Francisco.
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