10 Best Airbnb Vacation Rentals In St. Charles, Missouri - Updated 2022


If you’re mapping out your vacation in Missouri, don’t miss visiting the historic city of St. Charles, which is situated by the Missouri River. It was initially called Les Petites Cotes, which is French for “The Little Hills”, and it was founded by French Canadian explorer, Louis Blanchette. In this charming Missouri city, you’ll find many speciality stores, pretty parks, and recreational spots. Try their award-winning wines as you take in scenic views of the vineyards. To enjoy the best of this destination, be sure to stay at any of these best Airbnb vacation rentals in St. Charles, Missouri. Scroll down to know more!

1. Five-star stay in a private luxury suite (from USD 91)

Say goodbye five-star hotel stays because this private luxury suite will put a smile on your face from the moment you check-in. Located two blocks from Historic Main Street and a few minutes away from the upscale streets of Saint Charles, this Airbnb looks like a quaint home from the outside that opens to a classic chic setting. There is a queen bed and a pull out sofa that can fit three people comfortably. Sink into the plush linens facing a 55-inch (139.7-cm) television. Modern amenities such as a fridge, microwave, Keurig (hot drink dispenser), bathrobes, and board games are available too.

Luxury suite 2 blocks from Main St.
Saint Charles, Missouri, United States
163 reviews Superhost  Wifi Available
Entire rental unit 2 Beds 2 Guests 0 Bedrooms 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
the furnishings are terrific and the bed is very comfortable
even though i prefer a harder mattress i loved climbing in bed at night
the incredibly clean rooms were well appointed with all the amenities one could possible want
it was so comfortable and enjoyable it was hard to leave the room and stop binge-watching "catfish"
kimberly's place was immaculately clean and very welcoming
the space was beautifully decorated and was very clean
the bed was amazingly soft and warm and clean
her place is so clean comfy and it’s in the perfect location
we really enjoyed our stay it was exactly what we needed clean updated and comfortable
worth every penny great host and great room
i did get an opportunity to speak with kimberly she was gracious and friendly
kimberly was so responsive and an amazing host
kimberly was an excellent host going above and beyond
kimberly was an amazing host and we had an amazing time in st
great little place great location
you can not go wrong staying at this location
nice quite place close by everything in this area
amazing place in a great location and perfect place for two to stay
the location is perfect if you plan on visiting historic main street (would recommend walking if possible)
Read more reviews

2. Plush master suite at The Benton House (from USD 116)

Heading to St. Charles with your small family or fur babies? Maybe you’re hunting for a place to host your bridal party or birthday weekend? No matter what your requirement is, The Benton House is your answer. You’ll be close to the historic and happening hub. The gorgeous pastel master suite at the attic is large and homey too, complete with a good view of the outside. There is also another queen-sized bed in the second bedroom. Upon entry, be greeted by the open concept living area. The home is equipped with a fully functional kitchen, fenced-in backyard (perfect for dogs), laptop-friendly workspace, washer and dryer, baby cot, and barbecue grill.

The Benton House - With fenced yard!
Saint Charles, Missouri, United States
378 reviews Superhost  Wifi Available
Entire home 2 Beds 4 Guests 2 Bedrooms 1 Bathroom

Accommodates: 4

Top guest reviews
Amenities & Room:
overall the furniture was cute and comfortable and we felt at ease immediately
the space is thoughtfully put together and the beds were very comfortable
such a great town and an excellent comfortable airbnb
fun furnishings great location comfortable beds pleasant place to hangout
very clean and comfortable stay
very clean place exactly as advertised
the place was very clean
it was spotless and beautifully decorated
charming clean cottage with warm and responsive hosts
interaction with the host was easy and friendly
she was very responsive to my questions
the owner was extremely easy to work with and provided everything we needed
perfect little property you can tell the host really cares about because of all the little touches throughout
superb place to stay host is extremely accommodating
great location for walking to downtown
great location to old town st
the neighborhood was perfectly located a short walk from the historic st charles downtown
easy to walk to shopping and restaurants
charles plus it's in a safe location
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3. Fabulous apartment for a solo traveller (from USD 92)

It does not get closer than this. Located at the centre of St. Charles’ downtown, it is steps away from Katy Trail, Missouri River, and the buzz of the town. This one-bedroom apartment has a queen-sized bed with an IKEA sofa bed in the living area, perfect for two to four people. Peek out of the balcony to watch people pass by. Essentials such as a stove, refrigerator, cooking basics, microwave, and coffee maker are available too. If you don’t mind listening to loud music on weekends (free party music at your apartment) and can handle climbing stairs, this place is a gem.

Great Vibes on Main Street in Historic St. Charles
Saint Charles, Missouri, United States
267 reviews Superhost  Wifi Available
Entire rental unit 1 Bed 3 Guests 1 Bedroom 1 Bathroom

Accommodates: 3

Top guest reviews
Amenities & Room:
i was enchanted with the apartment and the amazing balcony views
shower was nice ac works perfectly
this is a cozy little spot with a beautiful balcony that overlooks the historic main street
very clean and an excellent location
clean and has everything you need for convenience
a nice shower head and clean bathroom a full kitchen and a pour over coffeepot
it is roomy and comfortable and it’s clean as a whistle
apartment was really nice and clean has everything i needed
he is an amazing host with great hospitality
great place and great host
amazing stay host was awesome and perfect spot on main street
host and a very easy to work with and responsive
michael was an amazing host
really cute apartment in a fantastic location
perfect location walking distance to everything we wanted
great location in the heart of downtown st
the location was perfect
michael's apartment is an awesome location
Read more reviews

4. Elegant home with a classic theme (from USD 130)

A home decorated to fit a classic modern theme, this guest house is at the heart of St. Charles and just 2 blocks away from the main street where approximately 100 gift shops beckon. Chill out at the backyard and take in the greenery (if you’re visiting during summertime) with a cuppa, and you might just catch sight of the occasional red fox. Park your car in free parking slots on the street and walk to all the sights close by. The facilities in this Airbnb include Wifi, iron, and cooking basics. Shoppers, you’ll be glad to know that you will be eligible for discounts at the shops for being a guest at this home.

Saint Charles, Missouri, United States
300 reviews Superhost  Wifi Available
Entire home 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
bed and sheets were super comfy
expect a very pleasant space with comfortable bed and amenities
full kitchen full bath even a nice front room with tv
most comfortable bed just a really great place all around
very clean very comfortable
extremely clean and fantastic touches
super clean as well
very clean and organized space
cozy clean with beautiful decor
she was an awesome host
host is warm welcoming and available while respecting guests' privacy
charlene was an amazing host
charlene was an amazing host
charlene was a good host
great location to everything
wonderful house location and hostess
great location easy walking to main st
great house in a great location
breakfast was great so close to main street
Read more reviews

5. Ideal bungalow for big groups (from USD 159)

If your company spells fun, you better be heading to this bungalow home with ample space for an entertaining night in or a jolly night out. Main Street is only 15 minutes away and lined with shops, restaurants, and events. The classic All-American home has an adequate supply of board games and DVDs. There is also a pool table and a fire pit. Other amenities include two televisions with cable, Netflix and a DVD player, washer and dryer, fully equipped kitchen, and bathroom essentials. Perfect for eight, there are four bedrooms with a queen bed in two, a double bed and two single beds respectively.

Sweet Escape Near Historic Main Street & MO River
Saint Charles, Missouri, United States
98 reviews Superhost  Wifi Available
Entire home 5 Beds 8 Guests 4 Bedrooms 1 Bathroom

Accommodates: 8

Top guest reviews
nice and clean very comfortable
beautiful home very clean well appointed cute neighborhood
very clean and comfortable will book for our boat show next year
christy is a great host she made sure we had everything we needed and responded instantly to questions
amazing host and and house neighbors where very nice and love the location
this place is very highly recommended if you are in the area
this is by far one of the best places i’ve stayed
Read more reviews

6. Autumn-inspired home with high ceilings (from USD 137)

The sepia-toned home will remind you of the autumnal charm, no matter the season you visit. It invokes a homey, I-can-stay-here-forever feeling. Located just steps away from Main Street, the one-bedroom home is blessed with natural light and high ceilings. With one queen bed and an air mattress, it is perfect for a party of four. If you ever get tired of eating at the many restaurants lined outside, the fully equipped kitchen allows you to cook up whatever you are craving. Other facilities include a television with access to Netflix, Hulu and more, a free WiFi, washer and dryer, and a laptop-friendly workspace.

The Ella Rose Guest Suite in Historic St Charles❤️
Saint Charles, Missouri, United States
170 reviews Superhost  Wifi Available
Entire rental unit 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
wifi free parking nice cozy touches
a bit of noise from the neighbors and the heater but overall our stay was enjoyable
hosts were very thoughtful and provided an air mattress for our son since there is only one bed
great value for a really clean spot
the place was very clean and convenient to historical main st
doug and kristi responded very quickly had a clean place and were very thoughtful with a wonderful welcome note
the house is so charming clean and amazingly close to everything in st
extremely clean beautiful touches to the home and doug & kristi were extremely responsive
the hosts were amazing and very accommodating
this place is great doug and kristi were kind and were great hosts
these hosts went the extra mile to make our stay feel like we were right at home
i recomended 100% there airbnb they are a super host
kristi was the best host and answered all of my messages quickly
super cute little place close to main street
cute space with a great location
such a close walk to beautiful historic st
doug & kristi place is very well located beautiful historic area
a beautiful place with a great location
Read more reviews

7. Impressive abode near attractions (from USD 178)

Check into this lovely one-bedroom home that is just a three-minute walk from Main Street. Ameristar Casino, Dorset Park, The Arc, and St. Charles History Museum is just a short walk away. The charming home is fitted with a fully functional kitchen (yes, there is a Keurig with its pods included), bathroom essentials, extra pillows and blankets, washer and dryer, WiFi, free parking (at the carport and on the driveway), and hairdryer. If you are not too busy exploring the town, take some time off in the privately fenced backyard. Although this place is amazing, it is not suitable for people with mobility issues and children younger than two.

The Rose Cottage -a short walk to Historic Main St
Saint Charles, Missouri, United States
203 reviews Superhost  Wifi Available
Entire cottage 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
my boys loved sleeping on the pull out couch which was surprisingly comfortable
great a/c for the hot days
we had everything we needed for our stay: sheets towels coffee maker and excellent a/c
awesome bed fantastic shower and fully appointed kitchen
the kitchen was great and had everything we needed to eat in most nights and the beds were comfy
very clean and amazing communication
everything was very clean and convenient
everything very friendly clean and details as advertised
the house is very clean and nicely decorated
it was very clean quiet and cozy
the hosts were very attentive and thoughtful
rhonda and robert are very great host
it was very easy to communicate with the hosts and they were very responsive
communication with the owner was super fast and they were very helpful
robert was a great host and made me feel very welcome
the location was fabulous
perfect location with all you need close by
great location short walk to main street
a wonderful location for st charles
the location was very nice - short distance to shops and restaurants; easy access to highway
Read more reviews

8. Spacious 100-year-old townhouse for seven guests (from USD 178)

If you are visiting with a large family, The Madison House is a 100-year-old townhouse that fits seven. Located at the heart of the Historic District of St. Charles, the 1,400-square-feet (130-square-metre) home is close to the city sights. If you are looking for a bigger place, book the unit next door and get to enter via the adjoining door. The amenities include a fully functional kitchen, washer and dryer, children’s books and toys, television, WiFi, and a travel crib. You will need to go up the stairs to access the rooms and hence, not suited for those who are disabled.

Saint Charles, Missouri, United States
126 reviews Superhost  Wifi Available
Entire townhouse 3 Beds 7 Guests 2 Bedrooms 2 Bathrooms

Accommodates: 7

Top guest reviews
clean and bright and comfortable
was very clean and a great place to stay for the night
john is a great host who is very responsive to questions
john was a great host and super accommodating
host is very good with communication
john is a great host and communication with him was quick and easy
john was helpful and friendly and made terrific suggestions for places to go in st charles
great location beautiful old st
nice house good location interesting stay
great place and great location within walking distance of coffee house and close to other restaurants
great location - just a half-mile walk to the missouri river/historic st
this space was great perfect location for us
Read more reviews

9. Instagram-worthy home for a party of 12 (from USD 325)

Quirky and quite large, this colourful bungalow has five bedrooms, six beds, and two bathrooms that fit twelve guests comfortably. Plan your stay with the family, friends, or plan a small-scale party. Just blocks away from Main Street, you’ll have access to all the goodies (shopping, food, and events) the town has to offer. The facilities include a fully equipped kitchen, television with access to Netflix, WiFi, and a popcorn machine. You probably cannot find another home around the area that has such gorgeous aesthetics. Once you enter the movie room, it is like being transported several decades back in time. If you are an art enthusiast, don’t miss booking this Airbnb.

Charming Bungalow in Historic St. Charles, MO
Saint Charles, Missouri, United States
93 reviews Superhost  Wifi Available
Entire home 6 Beds 12 Guests 5 Bedrooms 2 Bathrooms

Accommodates: 12

Top guest reviews
they were very kind and helpful
incredible decor and very thoughtful hosts
the host were awesome and quick we really appreciated them letting us into their home
there are plenty of spaces for people to sleep/stay the decor/aesthetic is stunning and the hosts are amazing
i hosted a bachelorette party here and it was perfect
a great place to stay
it’s a great deal for how many people it can sleep and it is in a fabulous location
Read more reviews

10. Gorgeous 150-year-old historic home

Staying in a historic home does not mean age-old amenities and rickety flooring. This private home is gorgeous on the outside and the inside. You’ll be walking distance away from an array of unique shops, restaurants, and historical sites. Be sure that you are mobile before you book as there are steps that lead you up to the unit. There is a queen bed, loveseat sofa sleeper, fully equipped kitchen, and a full bath with a walk-in shower. If you are driving, there is free parking on the premises. Other amenities include WiFi, extra pillows and blankets, hairdryer, and iron. If you’re lucky, you might even be served some snacks upon check-in!

Lovely private apartment in historic home
Saint Charles, Missouri, United States
143 reviews  Wifi Available
Entire rental unit 2 Beds 2 Guests 0 Bedrooms 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
the pull out couch was super comfortable
amazing amenities included a full kitchen for affordable eating or reheating leftovers
also many surprise extras were provided such as yummy muffins cold soda snacks and breakfast items
cozy well appointed studio in a lovely neighborhood filled with trees old brick homes and churches
the lovely room had thoughtful touches from a soft throw on the chair to mints
charles so clean and cozy
the apartment was very clean and well setup for our weekend in st
very clean i highly recommend this cozy stay
charles and very clean
the space was clean and the area was safe and cute
karin was a great host
karin was very quick and responsive to any questions
karin was a great communicator and host
karin was a great host and i highly recommend this airbnb
karin was a wonderful host to work with & we will definitely be back
nice location close to downtown st
it’s a great location to downtown st charles
an amazing space and location
great little place close to main street
a beautiful cozy apartment situated just off 5th street
Read more reviews

Never a dull moment at St. Charles, Missouri!

Explore St. Charles on your next trip to Missouri. There is always something going on, and the friendly locals welcome travellers to their festivals. Shop, dine and drink to your fill. At the end of the day, come home to one of the best Airbnbs in the heart of St. Charles.

Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.

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A concoction of oxymoronic attributes, Rachel Yeoh is a lazy overachiever. She writes for a living, sings when the sun goes down and runs a homemade granola company with whatever is left of her...Read more

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