15 Best Airbnb Vacation Rentals In St. Charles, Missouri - Updated 2023

| 5 min read

If you’re mapping out your vacation in Missouri, don’t miss visiting the historic city of St. Charles, which is situated by the Missouri River. It was initially called Les Petites Cotes, which is French for “The Little Hills”, and it was founded by French Canadian explorer, Louis Blanchette. In this charming Missouri city, you’ll find many speciality stores, pretty parks, and recreational spots. You can also look around at some of the historic hotels near St. Charles and try the award-winning wines from the scenic views of the community’s vineyards. But to enjoy the best of this destination, be sure to stay at any of these best Airbnb vacation rentals in St. Charles, Missouri.

1. Pop Luck's Guest Suite (from USD 114)

Pop Luck’s Guest Suite has high ceilings and an open living room that gives a relaxing ambiance to its guests. Those who love cooking meals can do their passion hassle-free with its complete set of kitchen appliances. Also, there is a 50-inch TV and WiFi available for entertainment.

Your appetite will stay satisfied during your stay here since this accommodation is accessible to coffee houses and creameries. For an enjoyable tour of the city, try renting a bicycle from Bike Stop Cafe.

Saint Charles, Missouri, United States
236 reviews   Superhost Wifi Available
ENTIRE RENTAL UNIT 2 Beds 4 Guests 1 Bedroom 1 Bathroom

Accommodates: 4

Top guest reviews
Amenities & Room:
bed was super comfy and appreciated the snacks
very clean and cozy
immaculately clean and neat
stay was as advertised clean and quiet
safe clean place responsive hosts
this is a wonderful spot to stay the place is clean spacious and beautifully decorated
lovely suite and amazing owners
the hosts were very friendly and helpful
nice extra touches from the hosts
we had a perfect experience and we have our hosts to thank
i message with the hosts about various topics and they are always quick respond and extremely helpful
great location close walk to main street
easy walk to historic downtown
the location is super close to main street in st
awesome location for historic st charles
the location to main street was awesome
Read more reviews

2. Chic retreat with a private patio (from USD 127)

This cosy bungalow features a private patio where you can drink your coffee or wine peacefully. Crafted for comfort, this single-level abode also gives you access to its full kitchen, washer, dryer, and TV with Netflix and Roku. You can also park your car freely within the premises.

By walking around the neighborhood, you can pass by majestic wedding venues. And if you love food, don’t forget to dine at Magpie’s Cafe and drop by Old Mill Stream Inn for some fine wines.

Saint Charles, Missouri, United States
131 reviews   Superhost Wifi Available
Entire bungalow 2 Beds 4 Guests 1 Bedroom 1 Bathroom

Accommodates: 4

Top guest reviews
clean and updated and comfortable
very clean peacefully decorated great bed linens towels and bathroom supplies
very clean & spacious has everything you need
apartment was clean and stocked with everything we needed
it was very clean and communication with kathy was great
great host very responsive flexible and helpful
she is the best airbnb host we’ve ever had
kathy was a great host and was easy to get ahold of
kathy is a wonderful host
kathy is a great host and available at a moment's notice
the location is great
the location was great
close to restaurants and a wonderful park
beautiful place loved the location - very close to downtown st
perfect location for exploring st charles
Read more reviews

3. Elegant apartment unit with a brick facade (from USD 209)

Situated in a five-unit building, this neatly looking studio space is perfect for a pair of travellers. All you need for a comfortable stay is inside the place, including a 55-inch TV, a plush queen-size bed, a full kitchen, and an air-conditioning unit. You can also use its off-street parking if you have a car.

Due to cat allergies, the owner only allows dogs in the vicinity, and bringing your fur friend means there’s a one-time 100 USD pet fee. Also, be mindful of your belongings since there’s a 25-USD charge plus shipping costs if you want them to be returned.

Saint Charles, Missouri, United States
157 reviews   Superhost Wifi Available
ENTIRE RENTAL UNIT 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
the apartment was stocked with everything i needed to be comfortable for a week-long stay
very clean very private
very comfortable and clean apartment
excellent location super clean and outstanding communication
jeffrey’s place is charming clean and contained of the necessities for our trip
very clean and comfortable for a work stay or weekend getaway
very responsive host
jeffrey was an excellent host who ensured we had everything we needed
jeffrey was a great host he communicated effectively and i had a wonderful experience
delightful stay nice neighborhood friendly courteous host
great host and any issue i had was resolved immediately
cute location close to everything
darling place close to downtown
i would recommend this location to any travelers
great space and great location
such a wonderful little studio close to the downtown of st
Read more reviews

4. The Beach House

Covering 400 sqft (37.16 sqm) of land area, The Beach House invites guests to its compact yet cozy space. With a full array of kitchen appliances, a bathroom, and portable fans, this can be your home away from home. For entertainment, you can also use the TV, WiFi, and board games available.

Only 15 minutes away from Main Street, this vacation rental is close to some of the notable attractions in the area. As you stay in this place, make sure to drop by Ameristar Casino, Katy Trail, and the Missouri River.

Saint Charles, Missouri, United States
123 reviews   Superhost Wifi Available
ENTIRE HOME 2 Beds 3 Guests 1 Bedroom 1 Bathroom

Accommodates: 3

Top guest reviews
the house was clean and comfortable
very clean and a safe neighborhood
great little place very clean
very comfortable clean and perfect for 1-2 guests
the place was cozy and clean
hosts were very easy to work with
the hosts are quick to respond and very helpful should you need anything
very comfortable and cozy bed hosts were very attentive with everything i needed
great location cozy home nice host was easy to check-in and no issues during our stay
polo and alyse are fantastic hosts and the place is incredibly charming
close to a very nice downtown shopping area
the location was fantastic
great little house and easy walking distance from the main st
good location and nice and quiet neighborhood
we loved the house so cute and location is very convenient to downtown
Read more reviews

5. Luxurious getaway with outdoor amenities (from USD 99)

Perfect for families or groups of friends, this modern rental has a stylish dining area that complements its fully equipped kitchen. The couch in its airy living room is a great spot to hang out with your loved ones. Moreover, kids will never get bored as board games are available along with TV and WiFi.

Renting the property gives you access to using four bicycles and two kayaks for an outdoor adventure, similar to when you’re staying in one of the glamping spots near St. Louis. Also, with only a 10-minute drive, you can reach the downtown area and pass by Marsala’s Market and Rue Royale Restaurant.

Saint Charles, Missouri, United States
34 reviews   Wifi Available
ENTIRE HOME 3 Beds 6 Guests 2 Bedrooms 2 Bathrooms

Accommodates: 6

Top guest reviews
Amenities & Room:
the space is comfortable
anne and john’s place was very clean
very clean & anne was super kind & helpful
everything was so clean
her home was clean and true to the pictures
they were superhosts great house great location great communication clean and perfect
host was very responsive and helpful
our host anne was very nice caring and informative
house was beautiful and the host was so nice and accommodating
the host was wonderful with communication
clean and new the host anne was great had great recommendations and was very nice
a great place to stay we loved the location & being in walking distance to town
love the community and easy to walk to shops
this was a fantastic location and host
this was such a cute place to stay… the house was great and the neighborhood was beautiful
we really enjoyed our stay at anne’s place
Read more reviews

6. Five-star stay in a private luxury suite (from USD 95)

Say goodbye five-star hotel stays because this private luxury suite will put a smile on your face from the moment you check-in. Located two blocks from Historic Main Street and a few minutes away from the upscale streets of Saint Charles, this Airbnb looks like a quaint home from the outside that opens to a classic chic setting. There is a queen bed and a pull out sofa that can fit three people comfortably. Sink into the plush linens facing a 55-inch (139.7-cm) television. Modern amenities such as a fridge, microwave, Keurig (hot drink dispenser), bathrobes, and board games are available too.

Saint Charles, Missouri, United States
190 reviews   Superhost Wifi Available
ENTIRE RENTAL UNIT 2 Beds 2 Guests 0 Bedrooms 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
the furnishings are terrific and the bed is very comfortable
even though i prefer a harder mattress i loved climbing in bed at night
the incredibly clean rooms were well appointed with all the amenities one could possible want
it was so comfortable and enjoyable it was hard to leave the room and stop binge-watching "catfish"
kimberly's place was immaculately clean and very welcoming
the space was beautifully decorated and was very clean
the bed was amazingly soft and warm and clean
her place is so clean comfy and it’s in the perfect location
we really enjoyed our stay it was exactly what we needed clean updated and comfortable
worth every penny great host and great room
i did get an opportunity to speak with kimberly she was gracious and friendly
kimberly was so responsive and an amazing host
kimberly was an excellent host going above and beyond
kimberly was an amazing host and we had an amazing time in st
great little place great location
you can not go wrong staying at this location
nice quite place close by everything in this area
amazing place in a great location and perfect place for two to stay
the location is perfect if you plan on visiting historic main street (would recommend walking if possible)
Read more reviews

7. Plush master suite at The Benton House (from USD 110)

Heading to the city with your small family or fur babies? Maybe you’re hunting for a place to host your bridal party or birthday weekend? No matter what your requirement is, The Benton House is your answer. You’ll be close to the historic and happening hub. The gorgeous pastel master suite at the attic is large and homey too, complete with a good view of the outside. This also has another queen-sized bed in the second bedroom. Upon entry, be greeted by the open concept living area. The home is equipped with a fully functional kitchen, fenced-in backyard (perfect for dogs), laptop-friendly workspace, washer and dryer, baby cot, and barbecue grill.

Saint Charles, Missouri, United States
479 reviews   Superhost Wifi Available
ENTIRE HOME 2 Beds 4 Guests 2 Bedrooms 1 Bathroom

Accommodates: 4

Top guest reviews
Amenities & Room:
overall the furniture was cute and comfortable and we felt at ease immediately
the space is thoughtfully put together and the beds were very comfortable
such a great town and an excellent comfortable airbnb
fun furnishings great location comfortable beds pleasant place to hangout
very clean and comfortable stay
very clean place exactly as advertised
the place was very clean
it was spotless and beautifully decorated
charming clean cottage with warm and responsive hosts
interaction with the host was easy and friendly
she was very responsive to my questions
the owner was extremely easy to work with and provided everything we needed
perfect little property you can tell the host really cares about because of all the little touches throughout
superb place to stay host is extremely accommodating
great location for walking to downtown
great location to old town st
the neighborhood was perfectly located a short walk from the historic st charles downtown
easy to walk to shopping and restaurants
charles plus it's in a safe location
Read more reviews

8. Fabulous apartment for a solo traveller

It does not get closer than this. Located at the centre of St. Charles’ downtown, it is steps away from Katy Trail, Missouri River, and the buzz of the town. This one-bedroom apartment has a queen-sized bed with an IKEA sofa bed in the living area, perfect for two to four people. Peek out of the balcony to watch people pass by. Essentials such as a stove, refrigerator, cooking basics, microwave, and coffee maker are available too. If you don’t mind listening to loud music on weekends (free party music at your apartment) and can handle climbing stairs, this place is a gem.

Saint Charles, Missouri, United States
267 reviews   Superhost Wifi Available
ENTIRE RENTAL UNIT 1 Bed 3 Guests 1 Bedroom 1 Bathroom

Accommodates: 3

Top guest reviews
Amenities & Room:
i was enchanted with the apartment and the amazing balcony views
shower was nice ac works perfectly
this is a cozy little spot with a beautiful balcony that overlooks the historic main street
very clean and an excellent location
clean and has everything you need for convenience
a nice shower head and clean bathroom a full kitchen and a pour over coffeepot
it is roomy and comfortable and it’s clean as a whistle
apartment was really nice and clean has everything i needed
he is an amazing host with great hospitality
great place and great host
amazing stay host was awesome and perfect spot on main street
host and a very easy to work with and responsive
michael was an amazing host
really cute apartment in a fantastic location
perfect location walking distance to everything we wanted
great location in the heart of downtown st
the location was perfect
michael's apartment is an awesome location
Read more reviews

9. Elegant home with a classic theme (from USD 125)

A home decorated to fit a classic modern theme, this guest house is at the heart of St. Charles and just 2 blocks away from the main street where approximately 100 gift shops beckon. Chill out at the backyard and take in the greenery (if you’re visiting during summertime) with a cuppa, and you might just catch sight of the occasional red fox. Park your car in free parking slots on the street and walk to all the sights close by. The facilities in this Airbnb include Wifi, iron, and cooking basics. Shoppers, you’ll be glad to know that you will be eligible for discounts at the shops for being a guest at this home.

Saint Charles, Missouri, United States
424 reviews   Superhost Wifi Available
ENTIRE HOME 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
bed and sheets were super comfy
expect a very pleasant space with comfortable bed and amenities
full kitchen full bath even a nice front room with tv
most comfortable bed just a really great place all around
very clean very comfortable
extremely clean and fantastic touches
super clean as well
very clean and organized space
cozy clean with beautiful decor
she was an awesome host
host is warm welcoming and available while respecting guests' privacy
charlene was an amazing host
charlene was an amazing host
charlene was a good host
great location to everything
wonderful house location and hostess
great location easy walking to main st
great house in a great location
breakfast was great so close to main street
Read more reviews

10. Ideal bungalow for big groups (from USD 154)

If your company spells fun, you better be heading to this bungalow home with ample space for an entertaining night in or a jolly night out. This spot is lined with shops, restaurants, and events. The classic All-American home has an adequate supply of board games and DVDs. Other amenities of this Airbnb vacation rental with a pool table in St. Charles include two televisions with cable, a fire pit, Netflix and a DVD player, washer and dryer, fully equipped kitchen, and bathroom essentials. Perfect for eight, there are four bedrooms with a queen bed in two, a double bed and two single beds respectively.

Saint Charles, Missouri, United States
156 reviews   Superhost Wifi Available
ENTIRE HOME 5 Beds 8 Guests 4 Bedrooms 1 Bathroom

Accommodates: 8

Top guest reviews
nice and clean very comfortable
beautiful home very clean well appointed cute neighborhood
very clean and comfortable will book for our boat show next year
christy is a great host she made sure we had everything we needed and responded instantly to questions
amazing host and and house neighbors where very nice and love the location
this place is very highly recommended if you are in the area
this is by far one of the best places i’ve stayed
Read more reviews

11. Autumn-inspired home with high ceilings (from USD 101)

The sepia-toned home will remind you of the autumnal charm, no matter the season you visit. It invokes a homey, I-can-stay-here-forever feeling. This Airbnb vacation rental near Main Street in St. Charles is blessed with natural light and high ceilings. With one queen bed and an air mattress, it is perfect for a party of four. If you ever get tired of eating at the many restaurants lined outside, the fully equipped kitchen allows you to cook up whatever you are craving. Other facilities include a television with access to Netflix, Hulu and more, a free WiFi, washer and dryer, and a laptop-friendly workspace.

Saint Charles, Missouri, United States
226 reviews   Superhost Wifi Available
ENTIRE RENTAL UNIT 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
wifi free parking nice cozy touches
a bit of noise from the neighbors and the heater but overall our stay was enjoyable
hosts were very thoughtful and provided an air mattress for our son since there is only one bed
great value for a really clean spot
the place was very clean and convenient to historical main st
doug and kristi responded very quickly had a clean place and were very thoughtful with a wonderful welcome note
the house is so charming clean and amazingly close to everything in st
extremely clean beautiful touches to the home and doug & kristi were extremely responsive
the hosts were amazing and very accommodating
this place is great doug and kristi were kind and were great hosts
these hosts went the extra mile to make our stay feel like we were right at home
i recomended 100% there airbnb they are a super host
kristi was the best host and answered all of my messages quickly
super cute little place close to main street
cute space with a great location
such a close walk to beautiful historic st
doug & kristi place is very well located beautiful historic area
a beautiful place with a great location
Read more reviews

12. Impressive abode near attractions (from USD 139)

Check into this lovely one-bedroom home that is just a three-minute walk from Main Street. Ameristar Casino, Dorset Park, The Arc, and St. Charles History Museum is just a short walk away. The charming home is fitted with a fully functional kitchen (yes, there is a Keurig with its pods included), bathroom essentials, extra pillows and blankets, washer and dryer, WiFi, free parking (at the carport and on the driveway), and hairdryer. If you are not too busy exploring the town, take some time off in the privately fenced backyard. Although this place is amazing, it is not suitable for people with mobility issues and children younger than two.

Saint Charles, Missouri, United States
239 reviews   Superhost Wifi Available
Entire cottage 1 Bed 2 Guests 1 Bedroom 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
my boys loved sleeping on the pull out couch which was surprisingly comfortable
great a/c for the hot days
we had everything we needed for our stay: sheets towels coffee maker and excellent a/c
awesome bed fantastic shower and fully appointed kitchen
the kitchen was great and had everything we needed to eat in most nights and the beds were comfy
very clean and amazing communication
everything was very clean and convenient
everything very friendly clean and details as advertised
the house is very clean and nicely decorated
it was very clean quiet and cozy
the hosts were very attentive and thoughtful
rhonda and robert are very great host
it was very easy to communicate with the hosts and they were very responsive
communication with the owner was super fast and they were very helpful
robert was a great host and made me feel very welcome
the location was fabulous
perfect location with all you need close by
great location short walk to main street
a wonderful location for st charles
the location was very nice - short distance to shops and restaurants; easy access to highway
Read more reviews

13. Spacious 100-year-old townhouse for seven guests (from USD 158)

If you are visiting with a large family, The Madison House is a 100-year-old townhouse that fits seven. Located at the heart of the Historic District of St. Charles, the 1,400-square-feet (130-square-metre) home is close to the city sights. If you are looking for a bigger place, book the unit next door and get to enter via the adjoining door. The amenities include a fully functional kitchen, washer and dryer, children’s books and toys, television, WiFi, and a travel crib. You will need to go up the stairs to access the rooms and hence, not suited for those who are disabled.

Saint Charles, Missouri, United States
158 reviews   Wifi Available
Entire townhouse 3 Beds 7 Guests 2 Bedrooms 1 Bathroom

Accommodates: 7

Top guest reviews
clean and bright and comfortable
was very clean and a great place to stay for the night
john is a great host who is very responsive to questions
john was a great host and super accommodating
host is very good with communication
john is a great host and communication with him was quick and easy
john was helpful and friendly and made terrific suggestions for places to go in st charles
great location beautiful old st
nice house good location interesting stay
great place and great location within walking distance of coffee house and close to other restaurants
great location - just a half-mile walk to the missouri river/historic st
this space was great perfect location for us
Read more reviews

14. Instagram-worthy home for a party of 12 (from USD 332)

Quirky and quite large, this colourful bungalow has five bedrooms, six beds, and two bathrooms that fit twelve guests comfortably. Plan your stay with the family, friends, or plan a small-scale party. Just blocks away from Main Street, you’ll have access to all the goodies (shopping, food, and events) the town has to offer. The facilities include a fully equipped kitchen, television with access to Netflix, WiFi, and a popcorn machine. You probably cannot find another home around the area that has such gorgeous aesthetics. Once you enter the movie room, it is like being transported several decades back in time. If you are an art enthusiast, don’t miss booking this Airbnb.

Saint Charles, Missouri, United States
132 reviews   Superhost Wifi Available
ENTIRE HOME 6 Beds 10 Guests 5 Bedrooms 2 Bathrooms

Accommodates: 10

Top guest reviews
they were very kind and helpful
incredible decor and very thoughtful hosts
the host were awesome and quick we really appreciated them letting us into their home
there are plenty of spaces for people to sleep/stay the decor/aesthetic is stunning and the hosts are amazing
i hosted a bachelorette party here and it was perfect
a great place to stay
it’s a great deal for how many people it can sleep and it is in a fabulous location
Read more reviews

15. Gorgeous 150-year-old historic home

Staying in a historic home does not mean age-old amenities and rickety flooring. This private home is gorgeous on the outside and the inside. You’ll be walking distance away from an array of unique shops, restaurants, and historical sites. Be sure that you are mobile before you book as there are steps that lead you up to the unit. There is a queen bed, loveseat sofa sleeper, fully equipped kitchen, and a full bath with a walk-in shower. If you are driving, there is free parking on the premises. Other amenities include WiFi, extra pillows and blankets, hairdryer, and iron. If you’re lucky, you might even be served some snacks upon check-in!

Saint Charles, Missouri, United States
143 reviews   Wifi Available
ENTIRE RENTAL UNIT 2 Beds 2 Guests 0 Bedrooms 1 Bathroom

Accommodates: 2

Top guest reviews
Amenities & Room:
the pull out couch was super comfortable
amazing amenities included a full kitchen for affordable eating or reheating leftovers
also many surprise extras were provided such as yummy muffins cold soda snacks and breakfast items
cozy well appointed studio in a lovely neighborhood filled with trees old brick homes and churches
the lovely room had thoughtful touches from a soft throw on the chair to mints
charles so clean and cozy
the apartment was very clean and well setup for our weekend in st
very clean i highly recommend this cozy stay
charles and very clean
the space was clean and the area was safe and cute
karin was a great host
karin was very quick and responsive to any questions
karin was a great communicator and host
karin was a great host and i highly recommend this airbnb
karin was a wonderful host to work with & we will definitely be back
nice location close to downtown st
it’s a great location to downtown st charles
an amazing space and location
great little place close to main street
a beautiful cozy apartment situated just off 5th street
Read more reviews

Never a dull moment at St. Charles, Missouri!

Explore St. Charles on your next trip to Missouri. There is always something going on, and the friendly locals welcome travellers to their festivals. Shop, dine and drink to your fill. At the end of the day, come home to one of the best Airbnbs in the heart of St. Charles.

Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.


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A concoction of oxymoronic attributes, Rachel Yeoh is a lazy overachiever. She writes for a living, sings when the sun goes down and runs a homemade granola company with whatever is left of her...Read more

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