9 Handpicked Luxury Rentals In South Carolina, USA

Stephen
Contributing Writer
Updated
| 4 min read

South Carolina is an attractive state that’s endowed with charming natural beauty such as pristine lakes and beautiful mountains. It boasts a breathtaking coastline along the Atlantic Ocean that’s lined with gorgeous beaches, resorts, and eclectic oceanfront restaurants. The state is home to Charleston, a lovely city that’s famed for antebellum architecture and attractions such as Fort Sumter and Magnolia Plantation & Gardens. Myrtle Beach serves as a haven for beach aficionados who want to indulge in beach adventure and music shows. Golfers and wildlife lovers always find their way to Hilton Head Island. Need accommodations? Check out the best luxury rentals in South Carolina, USA, for an opulent stay.

We handpicked these listings carefully, considering (wherever possible) host status, recent guest reviews, location, accommodation type, prices, availability of dates, decor, and access to luxury services and amenities. The image galleries get refreshed with the latest updates regularly. They were last updated on October 28, 2025.

1. Nicklaus, Kiawah Island (from USD 5914)

Bring your extended family to this stunning oceanfront home in Kiawah Island for an exciting vacation. It has three levels that offer breathtaking ocean views. This state-of-the-art designer home comes with a stylish pool and a hot tub along with outdoor sitting and dining areas featuring a top-of-the-line Lynx gas grill. The interior is just divine, with stunning Lutron lightings.

The house comes with a fully equipped gourmet kitchen for easy preparation of meals and a Savant control system for entertainment. Kids will be supplied with beach toys.

Kiawah Island, SC, US
16 Guests 7 Bedrooms 6 Bathrooms

2. Estate on the Lake, Seneca (from USD 1007)

This is a lovely house that guarantees a pleasant stay as it boasts picturesque views of the lake. Perfect for multiple families, the house comes with seven bedrooms and seven bathrooms. It can comfortably accommodate a maximum of 18 guests.

The house offers a full gourmet kitchen, two bars, four fireplaces, four 65-inch HDTVs, a billiard room, and a state-of-the-art music system. You can sip drinks while relaxing in the private hot tub or enjoy romantic evenings by the built-in fire pit.

Seneca, South Carolina, United States
Wheelchair accessible Visual Aid: Braille
PRIVATE VACATION HOME 18 Guests 7 Bedrooms 6 Bathrooms

Top guest reviews
Host:
owner was very responsive and took care of everything
the property owner is friendly and responsive
excellent house to host reunion or reception party
the owner super nice he gave me all the info i needed and responded quickly each time
and the owner was very responsive and accommodating
Location:
perfect location with picturesque views
location was perfect this home has so much potential
Cleanliness:
the house was absolutely amazing everything was clean sanitized and smelled so fresh
the house was very clean and stocked with everything we could need
this is an awesome property everything was clean
Amenities & Room:
the kitchen is amazing we had 13 adults and 4 babies all under age 3
family and friends had a fun filled week enjoying the lake pool and pontoon boat
so many spaces to relax in and views of the river from almost every room
would definitely love to stay in the summer months to be able to enjoy the pool
the kids loved the pool the pontoon boat ran beautifully and we spent many hours on the lake
Read more reviews

3. Picturesque home with mountain views, Landrum (from USD 2926)

Are you traveling with a group of outdoor enthusiasts and are looking for accommodation in Landrum? This is a charming home that welcomes you to indulge in a thrilling outdoor experience. Offering 9 beds and 3.5 bathrooms, the home can easily host 14 adventurers.

The property has a huge covered patio with a fireplace, a TV, and a dining table. You can enjoy a relaxing dip in the hot tub that’s set by the woods. The house boasts magnificent mountain views. There’s also a basketball court and full-court pickleball at the property.

Landrum, South Carolina, United States
147 reviews   Airbnb superhost icon Superhost Wifi Available
Entire cabin 9 Beds 14 Guests 3 Bedrooms 3 Bathrooms

Accommodates: 14

Top guest reviews
Host:
we hope ashley will host us again
the hosts have pretty much thought of everything
amazing house and amazing hosts
ashley sent us really helpful information based on our family’s interests and our daughter’s age
the host offered us so many great ideas for family adventures dining etc
Location:
the location is perfect
great location amazing house and wonderful hosts
great place in the nc/sc mountains lots to do close by and a great place to relax and rest
also we couldn’t believe there was a great hike just a few hundred feet away across the street
this was a perfect place for our family to spend time together
Cleanliness:
super clean & spacious
the house was immaculately clean
this was such a nice place everything was exceptionally clean
the house is beautiful clean and has everything you need for your stay
the kitchen is beautiful and very well appointed the beds comfortable and the bathrooms pristine
Amenities & Room:
once inside the wifi was great
we especially loved the massive hot tub indoor and outdoor fireplace and that kitchen was incredible
the outdoor tv and fireplace were perfect for watching football games
we loved waking up to the sunrise and going to bed with the stars overhead
Read more reviews

4. Artsy beachfront home, Folly Beach (from USD 4385)

Indulge in a luxurious stay in this romantic, artsy house that’s located only two blocks from the beach. It boasts a beautifully landscaped tropical compound with a stunning porch. The porch is equipped with cozy sofas, a dining table, and a ceiling fan. Its interior features luxurious décor and gorgeous lights that ooze a romantic aura.

The house has a sleek kitchen furnished with high-quality appliances. You can wash off beach sand in the outdoor shower and relax in the Japanese soaking tub.

Folly Beach, South Carolina, United States
146 reviews   Airbnb superhost icon Superhost Wifi Available
ENTIRE HOME 7 Beds 7 Guests 3 Bedrooms 2 Bathrooms

Accommodates: 7

Top guest reviews
Host:
she was a great host who made sure we had everything we needed
she is such a wonderful host
outstanding experience great place and host
corrie is a great host—very responsive
corrie is a very kind and caring person who is interested in making sure your needs are met
Location:
super close to berts too
easy to walk to everything
amazing location- beach restaurants shopping and groceries are all in walking distance
this house is in a perfect location
perfect location quiet and super private
Cleanliness:
very clean so many extra towels well-equipped kitchen comfortable beds easy beach access — 5 stars all around
our family had a great time the location was perfect and the house was clean and charming
Amenities & Room:
such a great space - the beds were comfortable and the outdoor space is great for entertaining
Read more reviews

5. New beachfront home with a heated pool, North Myrtle Beach (from USD 683)

You are welcome to enjoy the beauty of North Myrtle Beach all day long when staying at this beach house. The house provides a heated pool and a hot tub to relax in.

You’ll have access to an outdoor kitchen where you can enjoy an evening barbeque while admiring the sunsets. There’s a golf cart to help you explore the beautiful neighborhood and the beach.

North Myrtle Beach, South Carolina, United States
94 reviews   Airbnb superhost icon Superhost Wifi Available
ENTIRE HOME 8 Beds 11 Guests 4 Bedrooms 5 Bathrooms

Accommodates: 11

Top guest reviews
Host:
the host caleb is wonderfully responsive
the property owner’s timely communication prior to our arrival was outstanding the availability to answer questions was excellent and immediate
great host from beginning to end easy to communicate with and very responsive
the elevator was super helpful taking our luggage and things up and down when arriving and leaving
caleb is a great host and we had fun time with family and friends
Location:
location is perfect- close to everything including the beach but still felt private and secluded
the beach is such a short walk away beautiful and not too crowded
restaurants pharmacy gas station shopping etc…you’re close to soooo much but don’t worry it’s super quiet
this property is gorgeous and in a prime location
the property was super kid friendly elegant very close to the beach and spacious
Cleanliness:
overall great experience house was clean and supported 10 people comfortably
the beds are super comfortable there is plenty of space whether inside or outside clean etc
Amenities & Room:
the view from the patio & pool was great
cozy home with amazing amenities - look forward to catching more sunsets from this deck
the outdoor pool and grill were particularly awesome
the pool and patio area are wonderful
that bathroom was simply amazing the tub the shower very spacious
Read more reviews

6. Luxurious lakefront home, Lexington (from USD 1576)

This home offers a tranquil stay with splendid views of Lake Murray. There are 4 bedrooms and 4 bathrooms, so the rental can easily accommodate 12 people. You’ll have access to a spacious and fully furnished kitchen for your cooking needs.

There are two kayaks for those who wish to explore the lake waters. You can enjoy an evening barbeque by the lakeside while admiring the romantic sunset. The property offers Wi-Fi, TVs, entertainment space, and a private dock.

Lexington, South Carolina, United States
164 reviews   Wifi Available
ENTIRE HOME 8 Beds 8 Guests 4 Bedrooms 4 Bathrooms

Accommodates: 8

Top guest reviews
Host:
the hosts were incredibly helpful
the host are prompt attentive and very nice
beautiful home and wonderful hosts
the hosts were also a pleasure- easy to communicate with and very helpful
Location:
beautiful location a real hidden gem
located on nice quiet cove
this place is superb great location and beautiful home
we will definitely be repeat guests of this location
absolutely beautiful and in such a convenient location
Cleanliness:
this place is everything clean beautiful just overall nice
this property is amazing perfectly maintained equipped and absolutely spotless
the lake was very clean and was not overcrowded
this beautiful home is organized and very clean
there were plenty of stocked necessities and the home was beautiful and clean
Read more reviews

7. Chester Farm

Stay in this lovely home that boasts a breathtaking design. Its interior is beautifully lit with candlelight fixtures and furnished with chic furniture and an indoor fireplace to keep you warm when the temperatures drop. The property has an opulent sitting room with a smart TV that’s subscribed to Apple TV. The glass doors allow natural light to filter in freely.

It has a state-of-the-art kitchen, five spectacular bedrooms, a saltwater pool, Wi-Fi, and security cameras. Free parking is also available.

Chester, South Carolina, United States
10 reviews   Wifi Available
ENTIRE HOME 9 Beds 12 Guests 5 Bedrooms 6 Bathrooms

Accommodates: 12

Top guest reviews
Cleanliness:
the house is very spacious and beautiful
Amenities & Room:
such a pretty place so much space outdoors amazing pools
Read more reviews

8. Ocean Jewel, Beach Lagoon

Sitting a few steps from the ocean, this beachfront home promises stunning vistas of the beach and ocean that guests can enjoy from the large windows. With 7 bedrooms and 10 bathrooms, the house can host 20 people. The balcony is where you might want to spend your mornings to admire the beautiful sunrises.

When the temperatures start rising, take a refreshing dip in the private pool with a hot tub. The beach is easily accessible via the home’s private boardwalk.

Hilton Head, SC, US
8 reviews  
House 20 Guests 7 Bedrooms 7 Bathrooms

Accommodates: 20
Minimum Nights: 7
Refund Policy : 100% refund if you cancel at least 30 days before check-in.

9. Beach Bliss, Isle of Palms

Located mere steps from the beach, this stunning house can accommodate 12 guests as it has 6 bedrooms. It also comes with a beautiful balcony where you can lounge and let your eyes feast on breathtaking ocean views. You’ll be offered luxury white bed linens and plush bath towels and you get to wake up to panoramic ocean views.

You can enjoy a barbeque on the deck or a refreshing dip in the pool during your free time. For beach fun, there are bicycles, chairs, carts, coolers, umbrellas, kayaks, and paddleboards for your use.

4 reviews   Wifi Available
House 12 Guests 6 Bedrooms 7 Bathrooms

Accommodates: 12
Minimum Nights: 0
Refund Policy : 100% refund if you cancel at least 180 days before check-in.

Top guest reviews
Location:
the positive: the location was perfect plenty of room for our family vacation
great house - big new nice awesome location
Read more reviews

South Carolina: a magical destination

South Carolina is a beautiful destination on the east coast of the United States that welcomes you to explore its irresistible natural beauty. From its gorgeous beaches to the lush state parks, there’s a lot to see. Book one of the above Airbnb vacation rentals and enjoy a magical stay in South Carolina.

Any must-sees we missed? Tell us about them in the comments section or write a post here to help out fellow travelers!
Disclosure: Trip101 selects the listings in our articles independently. Some of the listings in this article contain affiliate links.

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Stephen is an avid content writer with a passion for adventure. He enjoys traveling and has visited several countries around the world. So far, South Africa stands out as his most exciting...View profile

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